HCSGD entry for SLC7A6
1. General information
| Official gene symbol | SLC7A6 |
|---|---|
| Entrez ID | 9057 |
| Gene full name | solute carrier family 7 (amino acid transporter light chain, y+L system), member 6 |
| Other gene symbols | LAT-2 LAT3 y+LAT-2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0005887 | Integral component of plasma membrane | TAS | cellular_component |
| GO:0006461 | Protein complex assembly | TAS | biological_process |
| GO:0006520 | Cellular amino acid metabolic process | TAS | biological_process |
| GO:0006810 | Transport | TAS | biological_process |
| GO:0006811 | Ion transport | TAS | biological_process |
| GO:0006865 | Amino acid transport | TAS | biological_process |
| GO:0007596 | Blood coagulation | TAS | biological_process |
| GO:0015171 | Amino acid transmembrane transporter activity | IEA | molecular_function |
| GO:0015297 | Antiporter activity | IEA | molecular_function |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016323 | Basolateral plasma membrane | IEA | cellular_component |
| GO:0050900 | Leukocyte migration | TAS | biological_process |
| GO:0055085 | Transmembrane transport | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1404748110 | 0.1635430075 | 0.7528063072 | 0.7815438998 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2439024083 |
| GSE13712_SHEAR | Up | 0.1616181872 |
| GSE13712_STATIC | Up | 0.1743692977 |
| GSE19018 | Down | -0.8522862611 |
| GSE19899_A1 | Up | 0.0799489920 |
| GSE19899_A2 | Up | 0.6839388126 |
| PubMed_21979375_A1 | Up | 0.0699993613 |
| PubMed_21979375_A2 | Up | 1.3020204567 |
| GSE35957 | Up | 0.2866498237 |
| GSE36640 | Up | 0.2592558144 |
| GSE54402 | Up | 0.3300243512 |
| GSE9593 | Down | -0.2745380177 |
| GSE43922 | Up | 0.6338168419 |
| GSE24585 | Down | -0.6092744219 |
| GSE37065 | Down | -0.2178770628 |
| GSE28863_A1 | Down | -0.0233653560 |
| GSE28863_A2 | Down | -0.1857071095 |
| GSE28863_A3 | Down | -0.7355967033 |
| GSE28863_A4 | Up | 0.2480626485 |
| GSE48662 | Down | -0.2298248314 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-30a-3p | MIMAT0000088 | MIRT001761 | Luciferase reporter assay//qRT-PCR//Western blot | Functional MTI | 16239240 |
| hsa-miR-125b-5p | MIMAT0000423 | MIRT004987 | Microarray | Functional MTI (Weak) | 17891175 |
| hsa-miR-375 | MIMAT0000728 | MIRT020026 | Microarray | Functional MTI (Weak) | 20215506 |
| hsa-miR-98-5p | MIMAT0000096 | MIRT027832 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-193b-3p | MIMAT0002819 | MIRT041607 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
