HCSGD entry for CCNF


1. General information

Official gene symbolCCNF
Entrez ID899
Gene full namecyclin F
Other gene symbolsFBX1 FBXO1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000320Re-entry into mitotic cell cycleIEAbiological_process
GO:0001890Placenta developmentIEAbiological_process
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005814CentrioleIDAcellular_component
GO:0007067MitosisIEAbiological_process
GO:0010826Negative regulation of centrosome duplicationIDAbiological_process
GO:0016567Protein ubiquitinationIDAbiological_process
GO:0019005SCF ubiquitin ligase complexIDAcellular_component
GO:0031146SCF-dependent proteasomal ubiquitin-dependent protein catabolic processIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.99214595570.00438426730.99999024730.1348110981

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1084635509
GSE13712_SHEARUp0.0744732704
GSE13712_STATICUp0.3117826693
GSE19018Down-0.0975976633
GSE19899_A1Down-0.2552892592
GSE19899_A2Down-1.5000503923
PubMed_21979375_A1Down-0.6396564223
PubMed_21979375_A2Down-0.9747226442
GSE35957Down-1.2223772733
GSE36640Down-2.7220147741
GSE54402Down-0.3615527607
GSE9593Down-0.5265500187
GSE43922Up0.0539348093
GSE24585Down-0.0434698466
GSE37065Down-0.3640408698
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Down-0.3842897694

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-503-5pMIMAT0002874MIRT000643Luciferase reporter assayFunctional MTI19956200
hsa-miR-424-5pMIMAT0001341MIRT000653Luciferase reporter assayFunctional MTI19956200
hsa-let-7b-5pMIMAT0000063MIRT005061MicroarrayFunctional MTI (Weak)17699775
hsa-let-7b-5pMIMAT0000063MIRT005061CLASHFunctional MTI (Weak)23622248
hsa-miR-98-5pMIMAT0000096MIRT027780MicroarrayFunctional MTI (Weak)19088304
hsa-miR-423-5pMIMAT0004748MIRT038126CLASHFunctional MTI (Weak)23622248
hsa-miR-615-3pMIMAT0003283MIRT040085CLASHFunctional MTI (Weak)23622248
hsa-miR-324-3pMIMAT0000762MIRT042895CLASHFunctional MTI (Weak)23622248
hsa-let-7c-5pMIMAT0000064MIRT051739CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.