HCSGD entry for CCNF
1. General information
| Official gene symbol | CCNF |
|---|---|
| Entrez ID | 899 |
| Gene full name | cyclin F |
| Other gene symbols | FBX1 FBXO1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000320 | Re-entry into mitotic cell cycle | IEA | biological_process |
| GO:0001890 | Placenta development | IEA | biological_process |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005814 | Centriole | IDA | cellular_component |
| GO:0007067 | Mitosis | IEA | biological_process |
| GO:0010826 | Negative regulation of centrosome duplication | IDA | biological_process |
| GO:0016567 | Protein ubiquitination | IDA | biological_process |
| GO:0019005 | SCF ubiquitin ligase complex | IDA | cellular_component |
| GO:0031146 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9921459557 | 0.0043842673 | 0.9999902473 | 0.1348110981 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1084635509 |
| GSE13712_SHEAR | Up | 0.0744732704 |
| GSE13712_STATIC | Up | 0.3117826693 |
| GSE19018 | Down | -0.0975976633 |
| GSE19899_A1 | Down | -0.2552892592 |
| GSE19899_A2 | Down | -1.5000503923 |
| PubMed_21979375_A1 | Down | -0.6396564223 |
| PubMed_21979375_A2 | Down | -0.9747226442 |
| GSE35957 | Down | -1.2223772733 |
| GSE36640 | Down | -2.7220147741 |
| GSE54402 | Down | -0.3615527607 |
| GSE9593 | Down | -0.5265500187 |
| GSE43922 | Up | 0.0539348093 |
| GSE24585 | Down | -0.0434698466 |
| GSE37065 | Down | -0.3640408698 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Down | -0.3842897694 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-503-5p | MIMAT0002874 | MIRT000643 | Luciferase reporter assay | Functional MTI | 19956200 |
| hsa-miR-424-5p | MIMAT0001341 | MIRT000653 | Luciferase reporter assay | Functional MTI | 19956200 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT005061 | Microarray | Functional MTI (Weak) | 17699775 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT005061 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-98-5p | MIMAT0000096 | MIRT027780 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-423-5p | MIMAT0004748 | MIRT038126 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT040085 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-324-3p | MIMAT0000762 | MIRT042895 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7c-5p | MIMAT0000064 | MIRT051739 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
