HCSGD entry for CCKBR

1. General information

Official gene symbolCCKBR
Entrez ID887
Gene full namecholecystokinin B receptor
Other gene symbolsCCK-B CCK2R GASR
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001696Gastric acid secretionIEAbiological_process
GO:0004435Phosphatidylinositol phospholipase C activityTASmolecular_function
GO:0004951Cholecystokinin receptor activityTASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneICcellular_component
GO:0007166Cell surface receptor signaling pathwayNASbiological_process
GO:0007200Phospholipase C-activating G-protein coupled receptor signaling pathwayTASbiological_process
GO:0007204Positive regulation of cytosolic calcium ion concentrationIDAbiological_process
GO:0007586DigestionTASbiological_process
GO:0007600Sensory perceptionTASbiological_process
GO:0007631Feeding behaviorTASbiological_process
GO:0008152Metabolic processTASbiological_process
GO:0008283Cell proliferationTASbiological_process
GO:0008284Positive regulation of cell proliferationIDAbiological_process
GO:0015054Gastrin receptor activityIDA IEAmolecular_function
GO:0016021Integral component of membraneIEAcellular_component
GO:0031741Type B gastrin/cholecystokinin receptor bindingIDAmolecular_function
GO:0038188Cholecystokinin signaling pathwayTASbiological_process
GO:0042325Regulation of phosphorylationTASbiological_process
GO:0043551Regulation of phosphatidylinositol 3-kinase activityTASbiological_process
GO:00469351-phosphatidylinositol-3-kinase regulator activityTASmolecular_function
GO:0048565Digestive tract developmentIEAbiological_process
GO:0048732Gland developmentIEAbiological_process
GO:0050790Regulation of catalytic activityTASbiological_process
Entries Per Page
Displaying Page of

4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.62736918810.88702595650.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0310873747
GSE13712_SHEARDown-0.0476502259
GSE13712_STATICUp0.0556648386
GSE19018Up0.0144296701
GSE19899_A1Up0.1190595176
GSE19899_A2Down-0.0272156271
PubMed_21979375_A1Up0.0135247222
PubMed_21979375_A2Down-0.0161454086
GSE35957Up0.0298791009
GSE36640Up0.1455624412
GSE54402Down-0.0751687337
GSE9593Up0.1425485406
GSE43922Up0.0625407977
GSE24585Down-0.0960549689
GSE37065Down-0.1437324513
GSE28863_A1Up0.0456183507
GSE28863_A2Down-0.0908759152
GSE28863_A3Up0.2079495130
GSE28863_A4Up0.1415105779
GSE48662Up0.0959716666

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

PentagastrinDB00183 APRD01172

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-148b-3pMIMAT0000759MIRT005759Luciferase reporter assayFunctional MTI21205300
hsa-miR-148b-3pMIMAT0000759MIRT005759In situ hybridization//Luciferase reporter assay//qRT-PCR//Western blotFunctional MTI22020560
hsa-miR-148a-3pMIMAT0000243MIRT005898Luciferase reporter assay//MicroarrayFunctional MTI21168126
Entries Per Page
Displaying Page of
    • mirRecord

MicroRNA name

mirBase ID

Target site number

MiRNA mature ID

Test method inter

MiRNA regulation site

Reporter target site

Pubmed ID

hsa-miR-148b-3pMIMAT0000759NAhsa-miR-148b{Western blot}{overexpression by miRNA mimics tranfection}21205300
Entries Per Page
Displaying Page of

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.