HCSGD entry for SNX3
1. General information
| Official gene symbol | SNX3 |
|---|---|
| Entrez ID | 8724 |
| Gene full name | sorting nexin 3 |
| Other gene symbols | Grd19 MCOPS8 SDP3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005769 | Early endosome | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006897 | Endocytosis | TAS | biological_process |
| GO:0007154 | Cell communication | IEA | biological_process |
| GO:0010008 | Endosome membrane | IDA | cellular_component |
| GO:0015031 | Protein transport | IEA | biological_process |
| GO:0019903 | Protein phosphatase binding | IPI | molecular_function |
| GO:0032266 | Phosphatidylinositol-3-phosphate binding | IDA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2692508491 | 0.9411870332 | 0.9661062014 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2305579382 |
| GSE13712_SHEAR | Up | 0.0587202536 |
| GSE13712_STATIC | Up | 0.0962586362 |
| GSE19018 | Up | 0.2943362026 |
| GSE19899_A1 | Up | 0.2226031052 |
| GSE19899_A2 | Up | 0.1928482061 |
| PubMed_21979375_A1 | Up | 0.2412483570 |
| PubMed_21979375_A2 | Up | 0.0879880774 |
| GSE35957 | Down | -0.0055518026 |
| GSE36640 | Up | 0.3445260740 |
| GSE54402 | Up | 0.0267133458 |
| GSE9593 | Up | 0.3486210848 |
| GSE43922 | Down | -0.0476894336 |
| GSE24585 | Down | -0.0033235275 |
| GSE37065 | Down | -0.0300948980 |
| GSE28863_A1 | Down | -0.0055744577 |
| GSE28863_A2 | Up | 0.1914374819 |
| GSE28863_A3 | Down | -0.2171778248 |
| GSE28863_A4 | Up | 0.0507748606 |
| GSE48662 | Down | -0.3323757144 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| S,S-(2-Hydroxyethyl)Thiocysteine | DB04530 | EXPT00954 |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-30a-5p | MIMAT0000087 | MIRT028575 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-34a-5p | MIMAT0000255 | MIRT047345 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
