HCSGD entry for SNX3


1. General information

Official gene symbolSNX3
Entrez ID8724
Gene full namesorting nexin 3
Other gene symbolsGrd19 MCOPS8 SDP3
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005515Protein bindingIPImolecular_function
GO:0005737CytoplasmIDAcellular_component
GO:0005769Early endosomeIDAcellular_component
GO:0005829CytosolTAScellular_component
GO:0006897EndocytosisTASbiological_process
GO:0007154Cell communicationIEAbiological_process
GO:0010008Endosome membraneIDAcellular_component
GO:0015031Protein transportIEAbiological_process
GO:0019903Protein phosphatase bindingIPImolecular_function
GO:0032266Phosphatidylinositol-3-phosphate bindingIDAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.26925084910.94118703320.96610620141.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.2305579382
GSE13712_SHEARUp0.0587202536
GSE13712_STATICUp0.0962586362
GSE19018Up0.2943362026
GSE19899_A1Up0.2226031052
GSE19899_A2Up0.1928482061
PubMed_21979375_A1Up0.2412483570
PubMed_21979375_A2Up0.0879880774
GSE35957Down-0.0055518026
GSE36640Up0.3445260740
GSE54402Up0.0267133458
GSE9593Up0.3486210848
GSE43922Down-0.0476894336
GSE24585Down-0.0033235275
GSE37065Down-0.0300948980
GSE28863_A1Down-0.0055744577
GSE28863_A2Up0.1914374819
GSE28863_A3Down-0.2171778248
GSE28863_A4Up0.0507748606
GSE48662Down-0.3323757144

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

S,S-(2-Hydroxyethyl)ThiocysteineDB04530 EXPT00954

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-30a-5pMIMAT0000087MIRT028575ProteomicsFunctional MTI (Weak)18668040
hsa-miR-34a-5pMIMAT0000255MIRT047345CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.