HCSGD entry for CTSF

1. General information

Official gene symbolCTSF
Entrez ID8722
Gene full namecathepsin F
Other gene symbolsCATSF CLN13
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004197Cysteine-type endopeptidase activityTASmolecular_function
GO:0005764LysosomeTAScellular_component
GO:0006508ProteolysisIEAbiological_process
GO:0008219Cell deathIEAbiological_process
GO:0008234Cysteine-type peptidase activityIEAmolecular_function
GO:0019886Antigen processing and presentation of exogenous peptide antigen via MHC class IITASbiological_process
GO:0043202Lysosomal lumenTAScellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.07429177460.04871738920.57869089300.4128161571

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0818022224
GSE13712_SHEARDown-1.1938590611
GSE13712_STATICDown-0.1455531562
GSE19018Down-0.0502982933
GSE19899_A1Down-0.3553977919
GSE19899_A2Down-0.2152916103
PubMed_21979375_A1Down-1.0643933828
PubMed_21979375_A2Down-0.2370726562
GSE35957Up0.6305071730
GSE36640Up0.6906813549
GSE54402Down-0.7444629257
GSE9593Up0.7854796450
GSE43922Up0.0005158695
GSE24585Down-0.0620312325
GSE37065Up0.1298228885
GSE28863_A1Up0.8709855798
GSE28863_A2Up0.9546069689
GSE28863_A3Up0.3014030872
GSE28863_A4Down-0.5257663371
GSE48662Up0.6804520317

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

[1-(1-Methyl-4,5-Dioxo-Pent-2-Enylcarbamoyl)-2-Phenyl-Ethyl]-Carbamic Acid Benzyl EsterDB01810 EXPT00058
[1-(1-Benzyl-3-Hydroxy-2-Oxo-Propylcarbamoyl)-2-Phenyl-Ethyl]-Carbamic Acid Benzyl EsterDB01871 EXPT02989
4-Morpholin-4-Yl-Piperidine-1-Carboxylic Acid [1-(3-Benzenesulfonyl-1-Propyl-Allylcarbamoyl)-2-Phenylethyl]-AmideDB02243 EXPT02269
Benzoyl-Arginine-Alanine-Methyl KetoneDB03536 EXPT03294
WRR-99DB03573 EXPT02751
WRR-112DB03691 EXPT02790
HOMOPHENYLALANINYLMETHANEDB07913 -
BENZOYL-TYROSINE-ALANINE-METHYL KETONEDB08775 -

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT018210MicroarrayFunctional MTI (Weak)18185580
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.