HCSGD entry for CTSF


1. General information

Official gene symbolCTSF
Entrez ID8722
Gene full namecathepsin F
Other gene symbolsCATSF CLN13
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004197Cysteine-type endopeptidase activityTASmolecular_function
GO:0005764LysosomeTAScellular_component
GO:0006508ProteolysisIEAbiological_process
GO:0008219Cell deathIEAbiological_process
GO:0008234Cysteine-type peptidase activityIEAmolecular_function
GO:0019886Antigen processing and presentation of exogenous peptide antigen via MHC class IITASbiological_process
GO:0043202Lysosomal lumenTAScellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.07429177460.04871738920.57869089300.4128161571

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0818022224
GSE13712_SHEARDown-1.1938590611
GSE13712_STATICDown-0.1455531562
GSE19018Down-0.0502982933
GSE19899_A1Down-0.3553977919
GSE19899_A2Down-0.2152916103
PubMed_21979375_A1Down-1.0643933828
PubMed_21979375_A2Down-0.2370726562
GSE35957Up0.6305071730
GSE36640Up0.6906813549
GSE54402Down-0.7444629257
GSE9593Up0.7854796450
GSE43922Up0.0005158695
GSE24585Down-0.0620312325
GSE37065Up0.1298228885
GSE28863_A1Up0.8709855798
GSE28863_A2Up0.9546069689
GSE28863_A3Up0.3014030872
GSE28863_A4Down-0.5257663371
GSE48662Up0.6804520317

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

[1-(1-Methyl-4,5-Dioxo-Pent-2-Enylcarbamoyl)-2-Phenyl-Ethyl]-Carbamic Acid Benzyl EsterDB01810 EXPT00058
[1-(1-Benzyl-3-Hydroxy-2-Oxo-Propylcarbamoyl)-2-Phenyl-Ethyl]-Carbamic Acid Benzyl EsterDB01871 EXPT02989
4-Morpholin-4-Yl-Piperidine-1-Carboxylic Acid [1-(3-Benzenesulfonyl-1-Propyl-Allylcarbamoyl)-2-Phenylethyl]-AmideDB02243 EXPT02269
Benzoyl-Arginine-Alanine-Methyl KetoneDB03536 EXPT03294
WRR-99DB03573 EXPT02751
WRR-112DB03691 EXPT02790
HOMOPHENYLALANINYLMETHANEDB07913 -
BENZOYL-TYROSINE-ALANINE-METHYL KETONEDB08775 -

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT018210MicroarrayFunctional MTI (Weak)18185580
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.