HCSGD entry for S1PR4
1. General information
| Official gene symbol | S1PR4 |
|---|---|
| Entrez ID | 8698 |
| Gene full name | sphingosine-1-phosphate receptor 4 |
| Other gene symbols | EDG6 LPC1 S1P4 SLP4 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004930 | G-protein coupled receptor activity | TAS | molecular_function |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0005887 | Integral component of plasma membrane | TAS | cellular_component |
| GO:0006955 | Immune response | TAS | biological_process |
| GO:0007186 | G-protein coupled receptor signaling pathway | TAS | biological_process |
| GO:0007189 | Adenylate cyclase-activating G-protein coupled receptor signaling pathway | IEA | biological_process |
| GO:0007202 | Activation of phospholipase C activity | TAS | biological_process |
| GO:0007204 | Positive regulation of cytosolic calcium ion concentration | TAS | biological_process |
| GO:0008289 | Lipid binding | TAS | molecular_function |
| GO:0038036 | Sphingosine-1-phosphate receptor activity | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8450741005 | 0.4087686524 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1752036297 |
| GSE13712_SHEAR | Down | -0.4469103524 |
| GSE13712_STATIC | Down | -0.1899334755 |
| GSE19018 | Down | -0.0386494822 |
| GSE19899_A1 | Down | -0.0258853486 |
| GSE19899_A2 | Up | 0.1695904405 |
| PubMed_21979375_A1 | Down | -0.1486705058 |
| PubMed_21979375_A2 | Up | 0.0858870832 |
| GSE35957 | Up | 0.1133591667 |
| GSE36640 | Up | 0.1140036995 |
| GSE54402 | Up | 0.0438809040 |
| GSE9593 | Up | 0.0639049552 |
| GSE43922 | Down | -0.0414964805 |
| GSE24585 | Up | 0.1736201549 |
| GSE37065 | Down | -0.0990880261 |
| GSE28863_A1 | Down | -0.1813977284 |
| GSE28863_A2 | Down | -0.1851960248 |
| GSE28863_A3 | Up | 0.3664381850 |
| GSE28863_A4 | Up | 0.0284495580 |
| GSE48662 | Down | -0.0038600045 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
