HCSGD entry for S1PR4

1. General information

Official gene symbolS1PR4
Entrez ID8698
Gene full namesphingosine-1-phosphate receptor 4
Other gene symbolsEDG6 LPC1 S1P4 SLP4
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004930G-protein coupled receptor activityTASmolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0006955Immune responseTASbiological_process
GO:0007186G-protein coupled receptor signaling pathwayTASbiological_process
GO:0007189Adenylate cyclase-activating G-protein coupled receptor signaling pathwayIEAbiological_process
GO:0007202Activation of phospholipase C activityTASbiological_process
GO:0007204Positive regulation of cytosolic calcium ion concentrationTASbiological_process
GO:0008289Lipid bindingTASmolecular_function
GO:0038036Sphingosine-1-phosphate receptor activityIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.84507410050.40876865240.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1752036297
GSE13712_SHEARDown-0.4469103524
GSE13712_STATICDown-0.1899334755
GSE19018Down-0.0386494822
GSE19899_A1Down-0.0258853486
GSE19899_A2Up0.1695904405
PubMed_21979375_A1Down-0.1486705058
PubMed_21979375_A2Up0.0858870832
GSE35957Up0.1133591667
GSE36640Up0.1140036995
GSE54402Up0.0438809040
GSE9593Up0.0639049552
GSE43922Down-0.0414964805
GSE24585Up0.1736201549
GSE37065Down-0.0990880261
GSE28863_A1Down-0.1813977284
GSE28863_A2Down-0.1851960248
GSE28863_A3Up0.3664381850
GSE28863_A4Up0.0284495580
GSE48662Down-0.0038600045

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.