HCSGD entry for SLC4A4
1. General information
| Official gene symbol | SLC4A4 |
|---|---|
| Entrez ID | 8671 |
| Gene full name | solute carrier family 4, sodium bicarbonate cotransporter, member 4 |
| Other gene symbols | HNBC1 KNBC NBC1 NBC2 NBCe1-A SLC4A5 hhNMC pNBC |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005452 | Inorganic anion exchanger activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0005887 | Integral component of plasma membrane | TAS | cellular_component |
| GO:0006810 | Transport | TAS | biological_process |
| GO:0006811 | Ion transport | TAS | biological_process |
| GO:0008510 | Sodium:bicarbonate symporter activity | TAS | molecular_function |
| GO:0015698 | Inorganic anion transport | TAS | biological_process |
| GO:0015701 | Bicarbonate transport | TAS | biological_process |
| GO:0016323 | Basolateral plasma membrane | IEA | cellular_component |
| GO:0034220 | Ion transmembrane transport | TAS | biological_process |
| GO:0035725 | Sodium ion transmembrane transport | TAS | biological_process |
| GO:0055085 | Transmembrane transport | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9524447057 | 0.0015548345 | 0.9999902473 | 0.0760460111 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.4463540772 |
| GSE13712_SHEAR | Down | -0.0494599057 |
| GSE13712_STATIC | Up | 0.0580608386 |
| GSE19018 | Down | -0.6243369050 |
| GSE19899_A1 | Down | -0.8505477148 |
| GSE19899_A2 | Down | -1.0811525647 |
| PubMed_21979375_A1 | Down | -1.0519873286 |
| PubMed_21979375_A2 | Down | -1.3456041230 |
| GSE35957 | Up | 0.2017811409 |
| GSE36640 | Up | 1.5162447531 |
| GSE54402 | Down | -1.5367612415 |
| GSE9593 | Down | -0.2850436113 |
| GSE43922 | Down | -0.5912261251 |
| GSE24585 | Down | -0.2691877800 |
| GSE37065 | Down | -0.0533606146 |
| GSE28863_A1 | Down | -0.8065184066 |
| GSE28863_A2 | Down | -0.3594161623 |
| GSE28863_A3 | Down | -0.7998427392 |
| GSE28863_A4 | Down | -0.2195560372 |
| GSE48662 | Down | -0.2956022413 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
