HCSGD entry for SERPINA6


1. General information

Official gene symbolSERPINA6
Entrez ID866
Gene full nameserpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6
Other gene symbolsCBG
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004867Serine-type endopeptidase inhibitor activityIBAmolecular_function
GO:0005496Steroid bindingIDA IEAmolecular_function
GO:0005615Extracellular spaceIBA IEAcellular_component
GO:0006810TransportIEAbiological_process
GO:0008211Glucocorticoid metabolic processIEAbiological_process
GO:0010951Negative regulation of endopeptidase activityIBAbiological_process
GO:0030162Regulation of proteolysisIBAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.51717471220.66652553470.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.2021654324
GSE13712_SHEARUp0.0484682567
GSE13712_STATICDown-0.0499673088
GSE19018Up0.1529446043
GSE19899_A1Up0.0939255349
GSE19899_A2Up0.1062762131
PubMed_21979375_A1Down-0.0815963593
PubMed_21979375_A2Down-0.3107732397
GSE35957Up0.3633306479
GSE36640Down-0.0215422782
GSE54402Down-0.0925723433
GSE9593Up0.0598083719
GSE43922Up0.0138838903
GSE24585Up0.3260262506
GSE37065Up0.2316468215
GSE28863_A1Down-0.2113289708
GSE28863_A2Down-0.0547566740
GSE28863_A3Up0.0001094483
GSE28863_A4Up0.0599256374
GSE48662Up0.2930832230

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.