HCSGD entry for SERPINA6


1. General information

Official gene symbolSERPINA6
Entrez ID866
Gene full nameserpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6
Other gene symbolsCBG
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004867Serine-type endopeptidase inhibitor activityIBAmolecular_function
GO:0005496Steroid bindingIDA IEAmolecular_function
GO:0005615Extracellular spaceIBA IEAcellular_component
GO:0006810TransportIEAbiological_process
GO:0008211Glucocorticoid metabolic processIEAbiological_process
GO:0010951Negative regulation of endopeptidase activityIBAbiological_process
GO:0030162Regulation of proteolysisIBAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.51717471220.66652553470.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.2021654324
GSE13712_SHEARUp0.0484682567
GSE13712_STATICDown-0.0499673088
GSE19018Up0.1529446043
GSE19899_A1Up0.0939255349
GSE19899_A2Up0.1062762131
PubMed_21979375_A1Down-0.0815963593
PubMed_21979375_A2Down-0.3107732397
GSE35957Up0.3633306479
GSE36640Down-0.0215422782
GSE54402Down-0.0925723433
GSE9593Up0.0598083719
GSE43922Up0.0138838903
GSE24585Up0.3260262506
GSE37065Up0.2316468215
GSE28863_A1Down-0.2113289708
GSE28863_A2Down-0.0547566740
GSE28863_A3Up0.0001094483
GSE28863_A4Up0.0599256374
GSE48662Up0.2930832230

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.