HCSGD entry for RFXANK


1. General information

Official gene symbolRFXANK
Entrez ID8625
Gene full nameregulatory factor X-associated ankyrin-containing protein
Other gene symbolsANKRA1 BLS F14150_1 RFX-B
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003677DNA bindingIEAmolecular_function
GO:0003700Sequence-specific DNA binding transcription factor activityNASmolecular_function
GO:0003712Transcription cofactor activityTASmolecular_function
GO:0005634NucleusIEAcellular_component
GO:0005737CytoplasmIEAcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0007265Ras protein signal transductionIEAbiological_process
GO:0042826Histone deacetylase bindingIEAmolecular_function
GO:0045944Positive regulation of transcription from RNA polymerase II promoterIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.98174300750.02715057180.99999024730.3141081722

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1908406694
GSE13712_SHEARDown-0.2796005749
GSE13712_STATICUp0.1755398543
GSE19018Down-0.5529944547
GSE19899_A1Down-0.3646020850
GSE19899_A2Down-0.7951808712
PubMed_21979375_A1Up0.4232750930
PubMed_21979375_A2Down-1.2374171114
GSE35957Down-0.3636776109
GSE36640Down-0.1507695607
GSE54402Up0.0679459857
GSE9593Down-0.5321758883
GSE43922Down-0.0151805720
GSE24585Up0.0845613685
GSE37065Down-0.0911443886
GSE28863_A1Down-0.0232172415
GSE28863_A2Down-0.2475956456
GSE28863_A3Down-0.2498905770
GSE28863_A4Up0.0987049603
GSE48662Down-0.1808750718

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.


PubMed ID of the article

Sentenece the gene occurs

26952515The highest Ki-67, TPX2, TOP2A and hTERT mRNA expression levels were found in the highly proliferative BLs (18 specimens), in comparison with GISTs (137 specimens) and LMSs (9 specimens)
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