HCSGD entry for RFXANK
1. General information
| Official gene symbol | RFXANK |
|---|---|
| Entrez ID | 8625 |
| Gene full name | regulatory factor X-associated ankyrin-containing protein |
| Other gene symbols | ANKRA1 BLS F14150_1 RFX-B |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | NAS | molecular_function |
| GO:0003712 | Transcription cofactor activity | TAS | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0007265 | Ras protein signal transduction | IEA | biological_process |
| GO:0042826 | Histone deacetylase binding | IEA | molecular_function |
| GO:0045944 | Positive regulation of transcription from RNA polymerase II promoter | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9817430075 | 0.0271505718 | 0.9999902473 | 0.3141081722 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1908406694 |
| GSE13712_SHEAR | Down | -0.2796005749 |
| GSE13712_STATIC | Up | 0.1755398543 |
| GSE19018 | Down | -0.5529944547 |
| GSE19899_A1 | Down | -0.3646020850 |
| GSE19899_A2 | Down | -0.7951808712 |
| PubMed_21979375_A1 | Up | 0.4232750930 |
| PubMed_21979375_A2 | Down | -1.2374171114 |
| GSE35957 | Down | -0.3636776109 |
| GSE36640 | Down | -0.1507695607 |
| GSE54402 | Up | 0.0679459857 |
| GSE9593 | Down | -0.5321758883 |
| GSE43922 | Down | -0.0151805720 |
| GSE24585 | Up | 0.0845613685 |
| GSE37065 | Down | -0.0911443886 |
| GSE28863_A1 | Down | -0.0232172415 |
| GSE28863_A2 | Down | -0.2475956456 |
| GSE28863_A3 | Down | -0.2498905770 |
| GSE28863_A4 | Up | 0.0987049603 |
| GSE48662 | Down | -0.1808750718 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 26952515 | The highest Ki-67, TPX2, TOP2A and hTERT mRNA expression levels were found in the highly proliferative BLs (18 specimens), in comparison with GISTs (137 specimens) and LMSs (9 specimens) |
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