HCSGD entry for CAV3

1. General information

Official gene symbolCAV3
Entrez ID859
Gene full namecaveolin 3
Other gene symbolsLGMD1C LQT9 VIP-21 VIP21
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000139Golgi membraneIEAcellular_component
GO:0001778Plasma membrane repairIEAbiological_process
GO:0002027Regulation of heart rateIMPbiological_process
GO:0005246Calcium channel regulator activityIDAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005783Endoplasmic reticulumIDAcellular_component
GO:0005886Plasma membraneIDAcellular_component
GO:0005901CaveolaIEAcellular_component
GO:0006469Negative regulation of protein kinase activityISSbiological_process
GO:0006641Triglyceride metabolic processISSbiological_process
GO:0006897EndocytosisISSbiological_process
GO:0007009Plasma membrane organizationISSbiological_process
GO:0007015Actin filament organizationIEAbiological_process
GO:0007204Positive regulation of cytosolic calcium ion concentrationISSbiological_process
GO:0007517Muscle organ developmentTASbiological_process
GO:0007520Myoblast fusionIEAbiological_process
GO:0008016Regulation of heart contractionISSbiological_process
GO:0008022Protein C-terminus bindingIDAmolecular_function
GO:0008104Protein localizationISSbiological_process
GO:0008284Positive regulation of cell proliferationIEAbiological_process
GO:0009986Cell surfaceIEAcellular_component
GO:0010614Negative regulation of cardiac muscle hypertrophyIMPbiological_process
GO:0010831Positive regulation of myotube differentiationIEAbiological_process
GO:0014819Regulation of skeletal muscle contractionIMPbiological_process
GO:0016010Dystrophin-associated glycoprotein complexIDAcellular_component
GO:0016049Cell growthISSbiological_process
GO:0017015Regulation of transforming growth factor beta receptor signaling pathwayIEAbiological_process
GO:0017080Sodium channel regulator activityIDA IMPmolecular_function
GO:0019870Potassium channel inhibitor activityISSmolecular_function
GO:0030018Z discISScellular_component
GO:0030154Cell differentiationISSbiological_process
GO:0030315T-tubuleISScellular_component
GO:0031116Positive regulation of microtubule polymerizationISSbiological_process
GO:0031122Cytoplasmic microtubule organizationIEAbiological_process
GO:0031579Membrane raft organizationISSbiological_process
GO:0031594Neuromuscular junctionISScellular_component
GO:0031982VesicleIEAcellular_component
GO:0032403Protein complex bindingIDAmolecular_function
GO:0032947Protein complex scaffoldIPI ISSmolecular_function
GO:0033292T-tubule organizationTASbiological_process
GO:0038009Regulation of signal transduction by receptor internalizationIMPbiological_process
GO:0042383SarcolemmaIDAcellular_component
GO:0042391Regulation of membrane potentialIDAbiological_process
GO:0042593Glucose homeostasisISSbiological_process
GO:0042632Cholesterol homeostasisISSbiological_process
GO:0043014Alpha-tubulin bindingIEAmolecular_function
GO:0043407Negative regulation of MAP kinase activityIMPbiological_process
GO:0043409Negative regulation of MAPK cascadeISSbiological_process
GO:0044325Ion channel bindingIPImolecular_function
GO:0045121Membrane raftISScellular_component
GO:0045792Negative regulation of cell sizeIMPbiological_process
GO:0046716Muscle cell cellular homeostasisISSbiological_process
GO:0050998Nitric-oxide synthase bindingIEAmolecular_function
GO:0051001Negative regulation of nitric-oxide synthase activityISSbiological_process
GO:0051394Regulation of nerve growth factor receptor activityIMPbiological_process
GO:0051647Nucleus localizationIEAbiological_process
GO:0051896Regulation of protein kinase B signalingIEAbiological_process
GO:0051926Negative regulation of calcium ion transportIDAbiological_process
GO:0055013Cardiac muscle cell developmentIEAbiological_process
GO:0055117Regulation of cardiac muscle contractionIMPbiological_process
GO:0060299Negative regulation of sarcomere organizationIMPbiological_process
GO:0060307Regulation of ventricular cardiac muscle cell membrane repolarizationIMPbiological_process
GO:0060347Heart trabecula formationIEAbiological_process
GO:0060373Regulation of ventricular cardiac muscle cell membrane depolarizationIDAbiological_process
GO:0060762Regulation of branching involved in mammary gland duct morphogenesisIEAbiological_process
GO:0061052Negative regulation of cell growth involved in cardiac muscle cell developmentIEAbiological_process
GO:0070836Caveola assemblyIDAbiological_process
GO:0071253Connexin bindingIDAmolecular_function
GO:0072659Protein localization to plasma membraneISSbiological_process
GO:0086005Ventricular cardiac muscle cell action potentialISSbiological_process
GO:0090002Establishment of protein localization to plasma membraneIEAbiological_process
GO:0090279Regulation of calcium ion importIDAbiological_process
GO:1900744Regulation of p38MAPK cascadeIEAbiological_process
GO:1900825Regulation of membrane depolarization during cardiac muscle cell action potentialIMPbiological_process
GO:1901017Negative regulation of potassium ion transmembrane transporter activityISSbiological_process
GO:1901019Regulation of calcium ion transmembrane transporter activityIDAbiological_process
GO:1901380Negative regulation of potassium ion transmembrane transportISSbiological_process
GO:2000009Negative regulation of protein localization to cell surfaceNASbiological_process
GO:2000060Positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic processNASbiological_process
GO:2000649Regulation of sodium ion transmembrane transporter activityIDAbiological_process
GO:2001288Positive regulation of caveolin-mediated endocytosisIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.34331294400.88890785300.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1555925760
GSE13712_SHEARUp0.1640216058
GSE13712_STATICUp0.0686601716
GSE19018Up0.0649081402
GSE19899_A1Up0.1787680858
GSE19899_A2Up0.0259584351
PubMed_21979375_A1Up0.0066464256
PubMed_21979375_A2Down-0.0610693132
GSE35957Up0.0719130300
GSE36640Up0.0705529783
GSE54402Up0.0351104236
GSE9593Up0.0920063268
GSE43922Up0.0244253065
GSE24585Down-0.0805213888
GSE37065Up0.0676034614
GSE28863_A1Up0.1315327285
GSE28863_A2Up0.3212204546
GSE28863_A3Up0.2246905139
GSE28863_A4Up0.2333049717
GSE48662Down-0.2758417278

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.