HCSGD entry for CAV3

1. General information

Official gene symbolCAV3
Entrez ID859
Gene full namecaveolin 3
Other gene symbolsLGMD1C LQT9 VIP-21 VIP21
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000139Golgi membraneIEAcellular_component
GO:0001778Plasma membrane repairIEAbiological_process
GO:0002027Regulation of heart rateIMPbiological_process
GO:0005246Calcium channel regulator activityIDAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005783Endoplasmic reticulumIDAcellular_component
GO:0005886Plasma membraneIDAcellular_component
GO:0005901CaveolaIEAcellular_component
GO:0006469Negative regulation of protein kinase activityISSbiological_process
GO:0006641Triglyceride metabolic processISSbiological_process
GO:0006897EndocytosisISSbiological_process
GO:0007009Plasma membrane organizationISSbiological_process
GO:0007015Actin filament organizationIEAbiological_process
GO:0007204Positive regulation of cytosolic calcium ion concentrationISSbiological_process
GO:0007517Muscle organ developmentTASbiological_process
GO:0007520Myoblast fusionIEAbiological_process
GO:0008016Regulation of heart contractionISSbiological_process
GO:0008022Protein C-terminus bindingIDAmolecular_function
GO:0008104Protein localizationISSbiological_process
GO:0008284Positive regulation of cell proliferationIEAbiological_process
GO:0009986Cell surfaceIEAcellular_component
GO:0010614Negative regulation of cardiac muscle hypertrophyIMPbiological_process
GO:0010831Positive regulation of myotube differentiationIEAbiological_process
GO:0014819Regulation of skeletal muscle contractionIMPbiological_process
GO:0016010Dystrophin-associated glycoprotein complexIDAcellular_component
GO:0016049Cell growthISSbiological_process
GO:0017015Regulation of transforming growth factor beta receptor signaling pathwayIEAbiological_process
GO:0017080Sodium channel regulator activityIDA IMPmolecular_function
GO:0019870Potassium channel inhibitor activityISSmolecular_function
GO:0030018Z discISScellular_component
GO:0030154Cell differentiationISSbiological_process
GO:0030315T-tubuleISScellular_component
GO:0031116Positive regulation of microtubule polymerizationISSbiological_process
GO:0031122Cytoplasmic microtubule organizationIEAbiological_process
GO:0031579Membrane raft organizationISSbiological_process
GO:0031594Neuromuscular junctionISScellular_component
GO:0031982VesicleIEAcellular_component
GO:0032403Protein complex bindingIDAmolecular_function
GO:0032947Protein complex scaffoldIPI ISSmolecular_function
GO:0033292T-tubule organizationTASbiological_process
GO:0038009Regulation of signal transduction by receptor internalizationIMPbiological_process
GO:0042383SarcolemmaIDAcellular_component
GO:0042391Regulation of membrane potentialIDAbiological_process
GO:0042593Glucose homeostasisISSbiological_process
GO:0042632Cholesterol homeostasisISSbiological_process
GO:0043014Alpha-tubulin bindingIEAmolecular_function
GO:0043407Negative regulation of MAP kinase activityIMPbiological_process
GO:0043409Negative regulation of MAPK cascadeISSbiological_process
GO:0044325Ion channel bindingIPImolecular_function
GO:0045121Membrane raftISScellular_component
GO:0045792Negative regulation of cell sizeIMPbiological_process
GO:0046716Muscle cell cellular homeostasisISSbiological_process
GO:0050998Nitric-oxide synthase bindingIEAmolecular_function
GO:0051001Negative regulation of nitric-oxide synthase activityISSbiological_process
GO:0051394Regulation of nerve growth factor receptor activityIMPbiological_process
GO:0051647Nucleus localizationIEAbiological_process
GO:0051896Regulation of protein kinase B signalingIEAbiological_process
GO:0051926Negative regulation of calcium ion transportIDAbiological_process
GO:0055013Cardiac muscle cell developmentIEAbiological_process
GO:0055117Regulation of cardiac muscle contractionIMPbiological_process
GO:0060299Negative regulation of sarcomere organizationIMPbiological_process
GO:0060307Regulation of ventricular cardiac muscle cell membrane repolarizationIMPbiological_process
GO:0060347Heart trabecula formationIEAbiological_process
GO:0060373Regulation of ventricular cardiac muscle cell membrane depolarizationIDAbiological_process
GO:0060762Regulation of branching involved in mammary gland duct morphogenesisIEAbiological_process
GO:0061052Negative regulation of cell growth involved in cardiac muscle cell developmentIEAbiological_process
GO:0070836Caveola assemblyIDAbiological_process
GO:0071253Connexin bindingIDAmolecular_function
GO:0072659Protein localization to plasma membraneISSbiological_process
GO:0086005Ventricular cardiac muscle cell action potentialISSbiological_process
GO:0090002Establishment of protein localization to plasma membraneIEAbiological_process
GO:0090279Regulation of calcium ion importIDAbiological_process
GO:1900744Regulation of p38MAPK cascadeIEAbiological_process
GO:1900825Regulation of membrane depolarization during cardiac muscle cell action potentialIMPbiological_process
GO:1901017Negative regulation of potassium ion transmembrane transporter activityISSbiological_process
GO:1901019Regulation of calcium ion transmembrane transporter activityIDAbiological_process
GO:1901380Negative regulation of potassium ion transmembrane transportISSbiological_process
GO:2000009Negative regulation of protein localization to cell surfaceNASbiological_process
GO:2000060Positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic processNASbiological_process
GO:2000649Regulation of sodium ion transmembrane transporter activityIDAbiological_process
GO:2001288Positive regulation of caveolin-mediated endocytosisIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.34331294400.88890785300.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1555925760
GSE13712_SHEARUp0.1640216058
GSE13712_STATICUp0.0686601716
GSE19018Up0.0649081402
GSE19899_A1Up0.1787680858
GSE19899_A2Up0.0259584351
PubMed_21979375_A1Up0.0066464256
PubMed_21979375_A2Down-0.0610693132
GSE35957Up0.0719130300
GSE36640Up0.0705529783
GSE54402Up0.0351104236
GSE9593Up0.0920063268
GSE43922Up0.0244253065
GSE24585Down-0.0805213888
GSE37065Up0.0676034614
GSE28863_A1Up0.1315327285
GSE28863_A2Up0.3212204546
GSE28863_A3Up0.2246905139
GSE28863_A4Up0.2333049717
GSE48662Down-0.2758417278

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.