HCSGD entry for YBX3


1. General information

Official gene symbolYBX3
Entrez ID8531
Gene full nameY box binding protein 3
Other gene symbolsCSDA CSDA1 DBPA ZONAB
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000122Negative regulation of transcription from RNA polymerase II promoterTASbiological_process
GO:0001701In utero embryonic developmentIEAbiological_process
GO:0003690Double-stranded DNA bindingTASmolecular_function
GO:0003697Single-stranded DNA bindingIEAmolecular_function
GO:0003700Sequence-specific DNA binding transcription factor activityNASmolecular_function
GO:0003714Transcription corepressor activityTASmolecular_function
GO:0003730MRNA 3'-UTR bindingISSmolecular_function
GO:0005634NucleusISScellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005844PolysomeIEAcellular_component
GO:0005923Tight junctionISScellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0007283SpermatogenesisIEAbiological_process
GO:0008584Male gonad developmentIEAbiological_process
GO:0009409Response to coldTASbiological_process
GO:0009566FertilizationIEAbiological_process
GO:0017048Rho GTPase bindingISSmolecular_function
GO:0043066Negative regulation of apoptotic processIEAbiological_process
GO:0046622Positive regulation of organ growthIEAbiological_process
GO:0048471Perinuclear region of cytoplasmISScellular_component
GO:0048642Negative regulation of skeletal muscle tissue developmentIEAbiological_process
GO:0060547Negative regulation of necrotic cell deathIMPbiological_process
GO:00709353'-UTR-mediated mRNA stabilizationICbiological_process
GO:0071356Cellular response to tumor necrosis factorIMPbiological_process
GO:0071474Cellular hyperosmotic responseIMPbiological_process
GO:1902219Negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stressIMPbiological_process
GO:2000767Positive regulation of cytoplasmic translationISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.17103875990.87873012040.81339940381.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0792048308
GSE13712_SHEARDown-0.0934675934
GSE13712_STATICUp0.0178611920
GSE19018Up0.1810166188
GSE19899_A1Up0.1702037580
GSE19899_A2Up0.3853409085
PubMed_21979375_A1Up1.5225237101
PubMed_21979375_A2Down-0.0255086806
GSE35957Up0.0312308309
GSE36640Up0.1481483456
GSE54402Down-0.1692956688
GSE9593Up0.1260482888
GSE43922Up0.1518362492
GSE24585Down-0.5902215531
GSE37065Up0.1150287092
GSE28863_A1Up0.1694451287
GSE28863_A2Up0.1900756921
GSE28863_A3Down-0.1409637207
GSE28863_A4Up0.0996409791
GSE48662Up0.0021506125

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-155-5pMIMAT0000646MIRT020521ProteomicsFunctional MTI (Weak)18668040
hsa-miR-124-3pMIMAT0000422MIRT022125ProteomicsFunctional MTI (Weak)18668037
hsa-miR-30a-5pMIMAT0000087MIRT028402ProteomicsFunctional MTI (Weak)18668040
hsa-miR-16-5pMIMAT0000069MIRT031397ProteomicsFunctional MTI (Weak)18668040
hsa-miR-652-3pMIMAT0003322MIRT039503CLASHFunctional MTI (Weak)23622248
hsa-miR-193b-3pMIMAT0002819MIRT041350CLASHFunctional MTI (Weak)23622248
hsa-miR-100-5pMIMAT0000098MIRT048561CLASHFunctional MTI (Weak)23622248
hsa-miR-92a-3pMIMAT0000092MIRT049114CLASHFunctional MTI (Weak)23622248
hsa-miR-18a-5pMIMAT0000072MIRT050665CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.