HCSGD entry for YBX3


1. General information

Official gene symbolYBX3
Entrez ID8531
Gene full nameY box binding protein 3
Other gene symbolsCSDA CSDA1 DBPA ZONAB
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000122Negative regulation of transcription from RNA polymerase II promoterTASbiological_process
GO:0001701In utero embryonic developmentIEAbiological_process
GO:0003690Double-stranded DNA bindingTASmolecular_function
GO:0003697Single-stranded DNA bindingIEAmolecular_function
GO:0003700Sequence-specific DNA binding transcription factor activityNASmolecular_function
GO:0003714Transcription corepressor activityTASmolecular_function
GO:0003730MRNA 3'-UTR bindingISSmolecular_function
GO:0005634NucleusISScellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005844PolysomeIEAcellular_component
GO:0005923Tight junctionISScellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0007283SpermatogenesisIEAbiological_process
GO:0008584Male gonad developmentIEAbiological_process
GO:0009409Response to coldTASbiological_process
GO:0009566FertilizationIEAbiological_process
GO:0017048Rho GTPase bindingISSmolecular_function
GO:0043066Negative regulation of apoptotic processIEAbiological_process
GO:0046622Positive regulation of organ growthIEAbiological_process
GO:0048471Perinuclear region of cytoplasmISScellular_component
GO:0048642Negative regulation of skeletal muscle tissue developmentIEAbiological_process
GO:0060547Negative regulation of necrotic cell deathIMPbiological_process
GO:00709353'-UTR-mediated mRNA stabilizationICbiological_process
GO:0071356Cellular response to tumor necrosis factorIMPbiological_process
GO:0071474Cellular hyperosmotic responseIMPbiological_process
GO:1902219Negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stressIMPbiological_process
GO:2000767Positive regulation of cytoplasmic translationISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.17103875990.87873012040.81339940381.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0792048308
GSE13712_SHEARDown-0.0934675934
GSE13712_STATICUp0.0178611920
GSE19018Up0.1810166188
GSE19899_A1Up0.1702037580
GSE19899_A2Up0.3853409085
PubMed_21979375_A1Up1.5225237101
PubMed_21979375_A2Down-0.0255086806
GSE35957Up0.0312308309
GSE36640Up0.1481483456
GSE54402Down-0.1692956688
GSE9593Up0.1260482888
GSE43922Up0.1518362492
GSE24585Down-0.5902215531
GSE37065Up0.1150287092
GSE28863_A1Up0.1694451287
GSE28863_A2Up0.1900756921
GSE28863_A3Down-0.1409637207
GSE28863_A4Up0.0996409791
GSE48662Up0.0021506125

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-155-5pMIMAT0000646MIRT020521ProteomicsFunctional MTI (Weak)18668040
hsa-miR-124-3pMIMAT0000422MIRT022125ProteomicsFunctional MTI (Weak)18668037
hsa-miR-30a-5pMIMAT0000087MIRT028402ProteomicsFunctional MTI (Weak)18668040
hsa-miR-16-5pMIMAT0000069MIRT031397ProteomicsFunctional MTI (Weak)18668040
hsa-miR-652-3pMIMAT0003322MIRT039503CLASHFunctional MTI (Weak)23622248
hsa-miR-193b-3pMIMAT0002819MIRT041350CLASHFunctional MTI (Weak)23622248
hsa-miR-100-5pMIMAT0000098MIRT048561CLASHFunctional MTI (Weak)23622248
hsa-miR-92a-3pMIMAT0000092MIRT049114CLASHFunctional MTI (Weak)23622248
hsa-miR-18a-5pMIMAT0000072MIRT050665CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.