HCSGD entry for GCM1


1. General information

Official gene symbolGCM1
Entrez ID8521
Gene full nameglial cells missing homolog 1 (Drosophila)
Other gene symbolsGCMA hGCMa
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003677DNA bindingIEAmolecular_function
GO:0003700Sequence-specific DNA binding transcription factor activityIDAmolecular_function
GO:0005634NucleusIEAcellular_component
GO:0005667Transcription factor complexIDAcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0006355Regulation of transcription, DNA-templatedIDAbiological_process
GO:0008134Transcription factor bindingIPImolecular_function
GO:0008270Zinc ion bindingIEAmolecular_function
GO:0009653Anatomical structure morphogenesisTASbiological_process
GO:0060018Astrocyte fate commitmentIEAbiological_process
GO:0060143Positive regulation of syncytium formation by plasma membrane fusionIEAbiological_process
GO:0060670Branching involved in labyrinthine layer morphogenesisIEAbiological_process
GO:0060706Cell differentiation involved in embryonic placenta developmentIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.57890215040.80423039400.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0779582212
GSE13712_SHEARDown-0.0513044167
GSE13712_STATICDown-0.2371908020
GSE19018Down-0.0061551288
GSE19899_A1Down-0.0456994039
GSE19899_A2Up0.1548852095
PubMed_21979375_A1Up0.0940069474
PubMed_21979375_A2Down-0.0348479498
GSE35957Up0.0072400548
GSE36640Up0.1162113322
GSE54402Down-0.0389026326
GSE9593Up0.0010093800
GSE43922Up0.0184138953
GSE24585Down-0.0647054249
GSE37065Down-0.0746869830
GSE28863_A1Down-0.0966628712
GSE28863_A2Up0.0293966697
GSE28863_A3Up0.1680515588
GSE28863_A4Up0.1454073278
GSE48662Up0.7945959329

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-19b-3pMIMAT0000074MIRT007272Luciferase reporter assayFunctional MTI23438603
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.