HCSGD entry for OFD1

1. General information

Official gene symbolOFD1
Entrez ID8481
Gene full nameoral-facial-digital syndrome 1
Other gene symbols71-7A CXorf5 JBTS10 RP23 SGBS2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000086G2/M transition of mitotic cell cycleTASbiological_process
GO:0000278Mitotic cell cycleTASbiological_process
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIEAcellular_component
GO:0005813CentrosomeIDAcellular_component
GO:0005814CentrioleIDA IEAcellular_component
GO:0005829CytosolTAScellular_component
GO:0005929CiliumIDA IEAcellular_component
GO:0007067MitosisISSbiological_process
GO:0007099Centriole replicationISSbiological_process
GO:0015630Microtubule cytoskeletonIDAcellular_component
GO:0034451Centriolar satelliteISScellular_component
GO:0036064Ciliary basal bodyIDAcellular_component
GO:0043014Alpha-tubulin bindingIEA ISSmolecular_function
GO:0043015Gamma-tubulin bindingIEA ISSmolecular_function
GO:0060271Cilium morphogenesisIEA ISSbiological_process
GO:0060287Epithelial cilium movement involved in determination of left/right asymmetryIEA ISSbiological_process
GO:0090307Spindle assembly involved in mitosisISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.28895635040.75233469090.98687029971.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0797115604
GSE13712_SHEARUp0.7904026983
GSE13712_STATICUp0.4880078054
GSE19018Down-0.1792876524
GSE19899_A1Up0.1109266022
GSE19899_A2Up0.2836870960
PubMed_21979375_A1Up0.0195007798
PubMed_21979375_A2Up0.4299636357
GSE35957Down-0.1267918895
GSE36640Down-0.1118740434
GSE54402Down-0.1940982506
GSE9593Down-0.3828520670
GSE43922Down-0.0104930041
GSE24585Down-0.0668758841
GSE37065Down-0.0123707787
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Up0.2805232536

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-26b-5pMIMAT0000083MIRT029155MicroarrayFunctional MTI (Weak)19088304
hsa-miR-17-5pMIMAT0000070MIRT050901CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.