HCSGD entry for NSMAF


1. General information

Official gene symbolNSMAF
Entrez ID8439
Gene full nameneutral sphingomyelinase (N-SMase) activation associated factor
Other gene symbolsFAN
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005057Receptor signaling protein activityTASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005737CytoplasmTAScellular_component
GO:0006672Ceramide metabolic processTASbiological_process
GO:0007165Signal transductionTASbiological_process
GO:0016230Sphingomyelin phosphodiesterase activator activityIEAmolecular_function
GO:0035556Intracellular signal transductionTASbiological_process
GO:0043065Positive regulation of apoptotic processIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.76993217580.13363974390.99999024730.7037878551

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1677461423
GSE13712_SHEARUp0.2809090549
GSE13712_STATICUp0.1250651106
GSE19018Down-0.1003617287
GSE19899_A1Down-0.2305204669
GSE19899_A2Down-0.3709046637
PubMed_21979375_A1Down-0.3807710245
PubMed_21979375_A2Down-0.2296430132
GSE35957Up0.0757414299
GSE36640Down-0.5033059042
GSE54402Up0.1565277830
GSE9593Up0.3471817815
GSE43922Down-0.4524272369
GSE24585Down-0.3421868909
GSE37065Down-0.0996201874
GSE28863_A1Up0.1689247961
GSE28863_A2Up0.0224066285
GSE28863_A3Up0.1369023186
GSE28863_A4Down-0.0251767258
GSE48662Down-0.2295029575

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-124-3pMIMAT0000422MIRT022284MicroarrayFunctional MTI (Weak)18668037
hsa-miR-26b-5pMIMAT0000083MIRT028876MicroarrayFunctional MTI (Weak)19088304
hsa-miR-92a-3pMIMAT0000092MIRT049421CLASHFunctional MTI (Weak)23622248
hsa-miR-25-3pMIMAT0000081MIRT050349CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.