HCSGD entry for NSMAF
1. General information
| Official gene symbol | NSMAF |
|---|---|
| Entrez ID | 8439 |
| Gene full name | neutral sphingomyelinase (N-SMase) activation associated factor |
| Other gene symbols | FAN |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005057 | Receptor signaling protein activity | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | TAS | cellular_component |
| GO:0006672 | Ceramide metabolic process | TAS | biological_process |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0016230 | Sphingomyelin phosphodiesterase activator activity | IEA | molecular_function |
| GO:0035556 | Intracellular signal transduction | TAS | biological_process |
| GO:0043065 | Positive regulation of apoptotic process | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7699321758 | 0.1336397439 | 0.9999902473 | 0.7037878551 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1677461423 |
| GSE13712_SHEAR | Up | 0.2809090549 |
| GSE13712_STATIC | Up | 0.1250651106 |
| GSE19018 | Down | -0.1003617287 |
| GSE19899_A1 | Down | -0.2305204669 |
| GSE19899_A2 | Down | -0.3709046637 |
| PubMed_21979375_A1 | Down | -0.3807710245 |
| PubMed_21979375_A2 | Down | -0.2296430132 |
| GSE35957 | Up | 0.0757414299 |
| GSE36640 | Down | -0.5033059042 |
| GSE54402 | Up | 0.1565277830 |
| GSE9593 | Up | 0.3471817815 |
| GSE43922 | Down | -0.4524272369 |
| GSE24585 | Down | -0.3421868909 |
| GSE37065 | Down | -0.0996201874 |
| GSE28863_A1 | Up | 0.1689247961 |
| GSE28863_A2 | Up | 0.0224066285 |
| GSE28863_A3 | Up | 0.1369023186 |
| GSE28863_A4 | Down | -0.0251767258 |
| GSE48662 | Down | -0.2295029575 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT022284 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT028876 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049421 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-25-3p | MIMAT0000081 | MIRT050349 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
