HCSGD entry for LRRC8C
1. General information
| Official gene symbol | LRRC8C |
|---|---|
| Entrez ID | 84230 |
| Gene full name | leucine rich repeat containing 8 family, member C |
| Other gene symbols | AD158 FAD158 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005789 | Endoplasmic reticulum membrane | IEA | cellular_component |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1531335474 | 0.8776246153 | 0.7799638942 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0014165601 |
| GSE13712_SHEAR | Down | -0.0088787388 |
| GSE13712_STATIC | Up | 0.1030024412 |
| GSE19018 | Down | -0.0784468364 |
| GSE19899_A1 | Up | 0.5862509038 |
| GSE19899_A2 | Down | -0.1220776008 |
| PubMed_21979375_A1 | Up | 0.8112670319 |
| PubMed_21979375_A2 | Up | 0.2155625878 |
| GSE35957 | Down | -0.2164350656 |
| GSE36640 | Up | 0.0260411785 |
| GSE54402 | Up | 0.3037375540 |
| GSE9593 | Down | -0.1427839268 |
| GSE43922 | Up | 0.4309072857 |
| GSE24585 | Down | -0.0126471025 |
| GSE37065 | Up | 0.5818857926 |
| GSE28863_A1 | Up | 0.0548163685 |
| GSE28863_A2 | Down | -0.0635007307 |
| GSE28863_A3 | Up | 0.0619956809 |
| GSE28863_A4 | Up | 0.0061619116 |
| GSE48662 | Down | -0.2540298963 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-30a-5p | MIMAT0000087 | MIRT005169 | pSILAC//Proteomics;Other | Functional MTI (Weak) | 18668040 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT022568 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-1 | MIMAT0000416 | MIRT023754 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-1 | MIMAT0000416 | MIRT023754 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026398 | Microarray | Functional MTI (Weak) | 19074876 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
