HCSGD entry for LRRC8C


1. General information

Official gene symbolLRRC8C
Entrez ID84230
Gene full nameleucine rich repeat containing 8 family, member C
Other gene symbolsAD158 FAD158
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005789Endoplasmic reticulum membraneIEAcellular_component
GO:0016021Integral component of membraneIEAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.15313354740.87762461530.77996389421.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0014165601
GSE13712_SHEARDown-0.0088787388
GSE13712_STATICUp0.1030024412
GSE19018Down-0.0784468364
GSE19899_A1Up0.5862509038
GSE19899_A2Down-0.1220776008
PubMed_21979375_A1Up0.8112670319
PubMed_21979375_A2Up0.2155625878
GSE35957Down-0.2164350656
GSE36640Up0.0260411785
GSE54402Up0.3037375540
GSE9593Down-0.1427839268
GSE43922Up0.4309072857
GSE24585Down-0.0126471025
GSE37065Up0.5818857926
GSE28863_A1Up0.0548163685
GSE28863_A2Down-0.0635007307
GSE28863_A3Up0.0619956809
GSE28863_A4Up0.0061619116
GSE48662Down-0.2540298963

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-30a-5pMIMAT0000087MIRT005169pSILAC//Proteomics;OtherFunctional MTI (Weak)18668040
hsa-miR-124-3pMIMAT0000422MIRT022568MicroarrayFunctional MTI (Weak)18668037
hsa-miR-1MIMAT0000416MIRT023754ProteomicsFunctional MTI (Weak)18668040
hsa-miR-1MIMAT0000416MIRT023754MicroarrayFunctional MTI (Weak)18668037
hsa-miR-192-5pMIMAT0000222MIRT026398MicroarrayFunctional MTI (Weak)19074876
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.