HCSGD entry for TAF3
1. General information
| Official gene symbol | TAF3 |
|---|---|
| Entrez ID | 83860 |
| Gene full name | TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa |
| Other gene symbols | TAF140 TAFII-140 TAFII140 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000122 | Negative regulation of transcription from RNA polymerase II promoter | IDA | biological_process |
| GO:0002039 | P53 binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005669 | Transcription factor TFIID complex | IDA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0043433 | Negative regulation of sequence-specific DNA binding transcription factor activity | IDA | biological_process |
| GO:0051457 | Maintenance of protein location in nucleus | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0255306295 | 0.9603224536 | 0.3748866146 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3184236043 |
| GSE13712_SHEAR | Up | 0.1807089177 |
| GSE13712_STATIC | Up | 0.1782027546 |
| GSE19018 | Down | -0.4497329530 |
| GSE19899_A1 | Up | 0.0269642802 |
| GSE19899_A2 | Up | 0.6178989403 |
| PubMed_21979375_A1 | Up | 1.0236442448 |
| PubMed_21979375_A2 | Up | 0.6647675378 |
| GSE35957 | Down | -0.4648665773 |
| GSE36640 | Down | -0.0988887870 |
| GSE54402 | Down | -0.0684468729 |
| GSE9593 | Down | -0.2043451492 |
| GSE43922 | Up | 0.2918194292 |
| GSE24585 | Up | 0.3241968299 |
| GSE37065 | Up | 0.2027435848 |
| GSE28863_A1 | Up | 0.3925131888 |
| GSE28863_A2 | Up | 0.2070989297 |
| GSE28863_A3 | Up | 0.1438736823 |
| GSE28863_A4 | Up | 0.1942280497 |
| GSE48662 | Up | 0.7320051344 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-375 | MIMAT0000728 | MIRT019668 | Microarray | Functional MTI (Weak) | 20215506 |
| hsa-miR-1180-3p | MIMAT0005825 | MIRT035927 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
