HCSGD entry for TAF3


1. General information

Official gene symbolTAF3
Entrez ID83860
Gene full nameTAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa
Other gene symbolsTAF140 TAFII-140 TAFII140
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000122Negative regulation of transcription from RNA polymerase II promoterIDAbiological_process
GO:0002039P53 bindingIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005669Transcription factor TFIID complexIDAcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0008270Zinc ion bindingIEAmolecular_function
GO:0043433Negative regulation of sequence-specific DNA binding transcription factor activityIDAbiological_process
GO:0051457Maintenance of protein location in nucleusIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.02553062950.96032245360.37488661461.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.3184236043
GSE13712_SHEARUp0.1807089177
GSE13712_STATICUp0.1782027546
GSE19018Down-0.4497329530
GSE19899_A1Up0.0269642802
GSE19899_A2Up0.6178989403
PubMed_21979375_A1Up1.0236442448
PubMed_21979375_A2Up0.6647675378
GSE35957Down-0.4648665773
GSE36640Down-0.0988887870
GSE54402Down-0.0684468729
GSE9593Down-0.2043451492
GSE43922Up0.2918194292
GSE24585Up0.3241968299
GSE37065Up0.2027435848
GSE28863_A1Up0.3925131888
GSE28863_A2Up0.2070989297
GSE28863_A3Up0.1438736823
GSE28863_A4Up0.1942280497
GSE48662Up0.7320051344

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-375MIMAT0000728MIRT019668MicroarrayFunctional MTI (Weak)20215506
hsa-miR-1180-3pMIMAT0005825MIRT035927CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.