HCSGD entry for HIST1H2BC


1. General information

Official gene symbolHIST1H2BC
Entrez ID8347
Gene full namehistone cluster 1, H2bc
Other gene symbolsH2B.1 H2B/l H2BFL dJ221C16.3
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000786NucleosomeNAScellular_component
GO:0003677DNA bindingNASmolecular_function
GO:0005634NucleusIEAcellular_component
GO:0006334Nucleosome assemblyNASbiological_process
GO:0042742Defense response to bacteriumIEAbiological_process
GO:0046982Protein heterodimerization activityIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.00000685760.99982888190.01157777781.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up2.3558630027
GSE13712_SHEARUp3.0416054821
GSE13712_STATICUp1.4718166243
GSE19018Up0.4635435651
GSE19899_A1Up2.4828612428
GSE19899_A2Up4.2540523956
PubMed_21979375_A1Up2.3418189639
PubMed_21979375_A2Up3.8164361115
GSE35957Up1.1439131785
GSE36640Up5.5603179565
GSE54402Up1.3064588300
GSE9593Up1.5497186161
GSE43922--
GSE24585--
GSE37065--
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Up0.8061662698

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-98-5pMIMAT0000096MIRT027695MicroarrayFunctional MTI (Weak)19088304
hsa-miR-26b-5pMIMAT0000083MIRT030061MicroarrayFunctional MTI (Weak)19088304
hsa-miR-744-5pMIMAT0004945MIRT037389CLASHFunctional MTI (Weak)23622248
hsa-miR-296-3pMIMAT0004679MIRT038429CLASHFunctional MTI (Weak)23622248
hsa-miR-625-5pMIMAT0003294MIRT039589CLASHFunctional MTI (Weak)23622248
hsa-miR-320aMIMAT0000510MIRT044515CLASHFunctional MTI (Weak)23622248
hsa-miR-31-5pMIMAT0000089MIRT049862CLASHFunctional MTI (Weak)23622248
hsa-miR-16-5pMIMAT0000069MIRT051239CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.