HCSGD entry for FZD7

1. General information

Official gene symbolFZD7
Entrez ID8324
Gene full namefrizzled family receptor 7
Other gene symbolsFzE3
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001944Vasculature developmentIBAbiological_process
GO:0004930G-protein coupled receptor activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005737CytoplasmIBAcellular_component
GO:0005886Plasma membraneIDAcellular_component
GO:0006355Regulation of transcription, DNA-templatedIMPbiological_process
GO:0007199G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messengerIBAbiological_process
GO:0007223Wnt signaling pathway, calcium modulating pathwayIBAbiological_process
GO:0007409AxonogenesisIBAbiological_process
GO:0007420Brain developmentIBAbiological_process
GO:0008406Gonad developmentIBAbiological_process
GO:0010812Negative regulation of cell-substrate adhesionIMPbiological_process
GO:0014834Satellite cell maintenance involved in skeletal muscle regenerationIEAbiological_process
GO:0016021Integral component of membraneTAScellular_component
GO:0017147Wnt-protein bindingIPImolecular_function
GO:0019827Stem cell maintenanceIMPbiological_process
GO:0030165PDZ domain bindingIPImolecular_function
GO:0030182Neuron differentiationISSbiological_process
GO:0032589Neuron projection membraneIBAcellular_component
GO:0033077T cell differentiation in thymusIEAbiological_process
GO:0034446Substrate adhesion-dependent cell spreadingIEAbiological_process
GO:0035412Regulation of catenin import into nucleusIMPbiological_process
GO:0038031Non-canonical Wnt signaling pathway via JNK cascadeIMPbiological_process
GO:0042327Positive regulation of phosphorylationIDAbiological_process
GO:0042666Negative regulation of ectodermal cell fate specificationIMPbiological_process
GO:0042813Wnt-activated receptor activityIBAmolecular_function
GO:0045177Apical part of cellIBAcellular_component
GO:0045893Positive regulation of transcription, DNA-templatedIDA IMPbiological_process
GO:0046330Positive regulation of JNK cascadeICbiological_process
GO:0048103Somatic stem cell divisionIEAbiological_process
GO:0060054Positive regulation of epithelial cell proliferation involved in wound healingIMPbiological_process
GO:0060070Canonical Wnt signaling pathwayIDA IMPbiological_process
GO:0060231Mesenchymal to epithelial transitionIMPbiological_process
GO:0071300Cellular response to retinoic acidISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.72003689450.00016434030.99999024730.0232822581

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.8533863843
GSE13712_SHEARUp0.0817733350
GSE13712_STATICUp0.0497125343
GSE19018Down-0.6704820788
GSE19899_A1Down-3.2610382763
GSE19899_A2Down-2.6469726824
PubMed_21979375_A1Down-4.6549410344
PubMed_21979375_A2Down-3.2104005664
GSE35957Down-0.5638124117
GSE36640Down-0.0587245422
GSE54402Down-2.6080878786
GSE9593Down-0.6709532560
GSE43922Down-1.8770803820
GSE24585Up0.2490699734
GSE37065Up0.2433161511
GSE28863_A1Up1.3799204336
GSE28863_A2Up0.7931278529
GSE28863_A3Down-0.5384657584
GSE28863_A4Down-0.1693587826
GSE48662Down-0.2157415032

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-145-5pMIMAT0000437MIRT005690Luciferase reporter assayNon-Functional MTI20737575
hsa-miR-215-5pMIMAT0000272MIRT024428MicroarrayFunctional MTI (Weak)19074876
hsa-miR-192-5pMIMAT0000222MIRT026887MicroarrayFunctional MTI (Weak)19074876
hsa-miR-940MIMAT0004983MIRT036603CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.