HCSGD entry for FZD7

1. General information

Official gene symbolFZD7
Entrez ID8324
Gene full namefrizzled family receptor 7
Other gene symbolsFzE3
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001944Vasculature developmentIBAbiological_process
GO:0004930G-protein coupled receptor activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005737CytoplasmIBAcellular_component
GO:0005886Plasma membraneIDAcellular_component
GO:0006355Regulation of transcription, DNA-templatedIMPbiological_process
GO:0007199G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messengerIBAbiological_process
GO:0007223Wnt signaling pathway, calcium modulating pathwayIBAbiological_process
GO:0007409AxonogenesisIBAbiological_process
GO:0007420Brain developmentIBAbiological_process
GO:0008406Gonad developmentIBAbiological_process
GO:0010812Negative regulation of cell-substrate adhesionIMPbiological_process
GO:0014834Satellite cell maintenance involved in skeletal muscle regenerationIEAbiological_process
GO:0016021Integral component of membraneTAScellular_component
GO:0017147Wnt-protein bindingIPImolecular_function
GO:0019827Stem cell maintenanceIMPbiological_process
GO:0030165PDZ domain bindingIPImolecular_function
GO:0030182Neuron differentiationISSbiological_process
GO:0032589Neuron projection membraneIBAcellular_component
GO:0033077T cell differentiation in thymusIEAbiological_process
GO:0034446Substrate adhesion-dependent cell spreadingIEAbiological_process
GO:0035412Regulation of catenin import into nucleusIMPbiological_process
GO:0038031Non-canonical Wnt signaling pathway via JNK cascadeIMPbiological_process
GO:0042327Positive regulation of phosphorylationIDAbiological_process
GO:0042666Negative regulation of ectodermal cell fate specificationIMPbiological_process
GO:0042813Wnt-activated receptor activityIBAmolecular_function
GO:0045177Apical part of cellIBAcellular_component
GO:0045893Positive regulation of transcription, DNA-templatedIDA IMPbiological_process
GO:0046330Positive regulation of JNK cascadeICbiological_process
GO:0048103Somatic stem cell divisionIEAbiological_process
GO:0060054Positive regulation of epithelial cell proliferation involved in wound healingIMPbiological_process
GO:0060070Canonical Wnt signaling pathwayIDA IMPbiological_process
GO:0060231Mesenchymal to epithelial transitionIMPbiological_process
GO:0071300Cellular response to retinoic acidISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.72003689450.00016434030.99999024730.0232822581

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.8533863843
GSE13712_SHEARUp0.0817733350
GSE13712_STATICUp0.0497125343
GSE19018Down-0.6704820788
GSE19899_A1Down-3.2610382763
GSE19899_A2Down-2.6469726824
PubMed_21979375_A1Down-4.6549410344
PubMed_21979375_A2Down-3.2104005664
GSE35957Down-0.5638124117
GSE36640Down-0.0587245422
GSE54402Down-2.6080878786
GSE9593Down-0.6709532560
GSE43922Down-1.8770803820
GSE24585Up0.2490699734
GSE37065Up0.2433161511
GSE28863_A1Up1.3799204336
GSE28863_A2Up0.7931278529
GSE28863_A3Down-0.5384657584
GSE28863_A4Down-0.1693587826
GSE48662Down-0.2157415032

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-145-5pMIMAT0000437MIRT005690Luciferase reporter assayNon-Functional MTI20737575
hsa-miR-215-5pMIMAT0000272MIRT024428MicroarrayFunctional MTI (Weak)19074876
hsa-miR-192-5pMIMAT0000222MIRT026887MicroarrayFunctional MTI (Weak)19074876
hsa-miR-940MIMAT0004983MIRT036603CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.