HCSGD entry for CDC45


1. General information

Official gene symbolCDC45
Entrez ID8318
Gene full namecell division cycle 45
Other gene symbolsCDC45L CDC45L2 PORC-PI-1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000076DNA replication checkpointTASbiological_process
GO:0000082G1/S transition of mitotic cell cycleTASbiological_process
GO:0000083Regulation of transcription involved in G1/S transition of mitotic cell cycleTASbiological_process
GO:0000278Mitotic cell cycleTASbiological_process
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005654NucleoplasmTAScellular_component
GO:0005737CytoplasmIEAcellular_component
GO:0005813CentrosomeIDAcellular_component
GO:0006260DNA replicationTASbiological_process
GO:0006270DNA replication initiationIEAbiological_process
GO:0006271DNA strand elongation involved in DNA replicationTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.97619000800.00028895560.99999024730.0312987654

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.4440703913
GSE13712_SHEARDown-0.0244427316
GSE13712_STATICDown-0.2882889668
GSE19018Down-0.0560202890
GSE19899_A1Down-0.7768067986
GSE19899_A2Down-3.0264434082
PubMed_21979375_A1Down-0.6483654783
PubMed_21979375_A2Down-1.9298988235
GSE35957Down-1.5105243997
GSE36640Down-3.2366927576
GSE54402Down-0.3679279148
GSE9593Down-1.5464698727
GSE43922Down-0.8661579160
GSE24585Down-0.0535065728
GSE37065Down-0.6775342979
GSE28863_A1Down-0.2589890840
GSE28863_A2Up0.4024718751
GSE28863_A3Down-0.1221203308
GSE28863_A4Up0.3582960208
GSE48662Down-2.1728291015

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-455-3pMIMAT0004784MIRT037897CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.