HCSGD entry for CDC45
1. General information
| Official gene symbol | CDC45 |
|---|---|
| Entrez ID | 8318 |
| Gene full name | cell division cycle 45 |
| Other gene symbols | CDC45L CDC45L2 PORC-PI-1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000076 | DNA replication checkpoint | TAS | biological_process |
| GO:0000082 | G1/S transition of mitotic cell cycle | TAS | biological_process |
| GO:0000083 | Regulation of transcription involved in G1/S transition of mitotic cell cycle | TAS | biological_process |
| GO:0000278 | Mitotic cell cycle | TAS | biological_process |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0005813 | Centrosome | IDA | cellular_component |
| GO:0006260 | DNA replication | TAS | biological_process |
| GO:0006270 | DNA replication initiation | IEA | biological_process |
| GO:0006271 | DNA strand elongation involved in DNA replication | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9761900080 | 0.0002889556 | 0.9999902473 | 0.0312987654 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.4440703913 |
| GSE13712_SHEAR | Down | -0.0244427316 |
| GSE13712_STATIC | Down | -0.2882889668 |
| GSE19018 | Down | -0.0560202890 |
| GSE19899_A1 | Down | -0.7768067986 |
| GSE19899_A2 | Down | -3.0264434082 |
| PubMed_21979375_A1 | Down | -0.6483654783 |
| PubMed_21979375_A2 | Down | -1.9298988235 |
| GSE35957 | Down | -1.5105243997 |
| GSE36640 | Down | -3.2366927576 |
| GSE54402 | Down | -0.3679279148 |
| GSE9593 | Down | -1.5464698727 |
| GSE43922 | Down | -0.8661579160 |
| GSE24585 | Down | -0.0535065728 |
| GSE37065 | Down | -0.6775342979 |
| GSE28863_A1 | Down | -0.2589890840 |
| GSE28863_A2 | Up | 0.4024718751 |
| GSE28863_A3 | Down | -0.1221203308 |
| GSE28863_A4 | Up | 0.3582960208 |
| GSE48662 | Down | -2.1728291015 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-455-3p | MIMAT0004784 | MIRT037897 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
