HCSGD entry for NRIP1


1. General information

Official gene symbolNRIP1
Entrez ID8204
Gene full namenuclear receptor interacting protein 1
Other gene symbolsRIP140
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000118Histone deacetylase complexIEAcellular_component
GO:0000122Negative regulation of transcription from RNA polymerase II promoterIDA IEAbiological_process
GO:0001543Ovarian follicle ruptureIEAbiological_process
GO:0003713Transcription coactivator activityIDA NASmolecular_function
GO:0003714Transcription corepressor activityIDA IEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0019915Lipid storageIEAbiological_process
GO:0030331Estrogen receptor bindingIEA IPImolecular_function
GO:0030521Androgen receptor signaling pathwayNASbiological_process
GO:0035257Nuclear hormone receptor bindingIPImolecular_function
GO:0035259Glucocorticoid receptor bindingIPImolecular_function
GO:0042826Histone deacetylase bindingIEAmolecular_function
GO:0045893Positive regulation of transcription, DNA-templatedNASbiological_process
GO:0045944Positive regulation of transcription from RNA polymerase II promoterIDAbiological_process
GO:0046965Retinoid X receptor bindingIEAmolecular_function
GO:0050681Androgen receptor bindingNASmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.46568710920.01192415560.99999024730.2157083849

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1711924235
GSE13712_SHEARUp0.5906010803
GSE13712_STATICUp0.7735664615
GSE19018Down-0.1224129766
GSE19899_A1Down-1.0769737767
GSE19899_A2Down-0.0981095161
PubMed_21979375_A1Up0.5949578155
PubMed_21979375_A2Down-0.5998558228
GSE35957Down-0.5572263659
GSE36640Down-1.4327375024
GSE54402Up0.2293006109
GSE9593Down-1.0242290106
GSE43922Down-0.7495366092
GSE24585Down-0.2270078235
GSE37065Up0.3281996670
GSE28863_A1Up0.1718968263
GSE28863_A2Up0.3151894563
GSE28863_A3Down-0.9892815165
GSE28863_A4Up0.0933193187
GSE48662Down-0.7157197182

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

4-HYDROXY-N'-(4-ISOPROPYLBENZYL)BENZOHYDRAZIDEDB06884 -

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-590-3pMIMAT0004801MIRT016179SequencingFunctional MTI (Weak)20371350
hsa-miR-24-3pMIMAT0000080MIRT030442MicroarrayFunctional MTI (Weak)19748357
hsa-miR-615-3pMIMAT0003283MIRT040328CLASHFunctional MTI (Weak)23622248
hsa-miR-15b-5pMIMAT0000417MIRT046539CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.