HCSGD entry for NRIP1
1. General information
| Official gene symbol | NRIP1 |
|---|---|
| Entrez ID | 8204 |
| Gene full name | nuclear receptor interacting protein 1 |
| Other gene symbols | RIP140 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000118 | Histone deacetylase complex | IEA | cellular_component |
| GO:0000122 | Negative regulation of transcription from RNA polymerase II promoter | IDA IEA | biological_process |
| GO:0001543 | Ovarian follicle rupture | IEA | biological_process |
| GO:0003713 | Transcription coactivator activity | IDA NAS | molecular_function |
| GO:0003714 | Transcription corepressor activity | IDA IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0019915 | Lipid storage | IEA | biological_process |
| GO:0030331 | Estrogen receptor binding | IEA IPI | molecular_function |
| GO:0030521 | Androgen receptor signaling pathway | NAS | biological_process |
| GO:0035257 | Nuclear hormone receptor binding | IPI | molecular_function |
| GO:0035259 | Glucocorticoid receptor binding | IPI | molecular_function |
| GO:0042826 | Histone deacetylase binding | IEA | molecular_function |
| GO:0045893 | Positive regulation of transcription, DNA-templated | NAS | biological_process |
| GO:0045944 | Positive regulation of transcription from RNA polymerase II promoter | IDA | biological_process |
| GO:0046965 | Retinoid X receptor binding | IEA | molecular_function |
| GO:0050681 | Androgen receptor binding | NAS | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4656871092 | 0.0119241556 | 0.9999902473 | 0.2157083849 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1711924235 |
| GSE13712_SHEAR | Up | 0.5906010803 |
| GSE13712_STATIC | Up | 0.7735664615 |
| GSE19018 | Down | -0.1224129766 |
| GSE19899_A1 | Down | -1.0769737767 |
| GSE19899_A2 | Down | -0.0981095161 |
| PubMed_21979375_A1 | Up | 0.5949578155 |
| PubMed_21979375_A2 | Down | -0.5998558228 |
| GSE35957 | Down | -0.5572263659 |
| GSE36640 | Down | -1.4327375024 |
| GSE54402 | Up | 0.2293006109 |
| GSE9593 | Down | -1.0242290106 |
| GSE43922 | Down | -0.7495366092 |
| GSE24585 | Down | -0.2270078235 |
| GSE37065 | Up | 0.3281996670 |
| GSE28863_A1 | Up | 0.1718968263 |
| GSE28863_A2 | Up | 0.3151894563 |
| GSE28863_A3 | Down | -0.9892815165 |
| GSE28863_A4 | Up | 0.0933193187 |
| GSE48662 | Down | -0.7157197182 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| 4-HYDROXY-N'-(4-ISOPROPYLBENZYL)BENZOHYDRAZIDE | DB06884 | - |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-590-3p | MIMAT0004801 | MIRT016179 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-24-3p | MIMAT0000080 | MIRT030442 | Microarray | Functional MTI (Weak) | 19748357 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT040328 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-15b-5p | MIMAT0000417 | MIRT046539 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
