HCSGD entry for CAMK2A
1. General information
Official gene symbol | CAMK2A |
---|---|
Entrez ID | 815 |
Gene full name | calcium/calmodulin-dependent protein kinase II alpha |
Other gene symbols | CAMKA |
Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
---|---|---|---|
GO:0000082 | G1/S transition of mitotic cell cycle | IEA | biological_process |
GO:0004674 | Protein serine/threonine kinase activity | IEA | molecular_function |
GO:0004683 | Calmodulin-dependent protein kinase activity | IEA | molecular_function |
GO:0005515 | Protein binding | IPI | molecular_function |
GO:0005516 | Calmodulin binding | IEA | molecular_function |
GO:0005524 | ATP binding | IEA | molecular_function |
GO:0005654 | Nucleoplasm | TAS | cellular_component |
GO:0005829 | Cytosol | TAS | cellular_component |
GO:0005886 | Plasma membrane | TAS | cellular_component |
GO:0006468 | Protein phosphorylation | IDA | biological_process |
GO:0006816 | Calcium ion transport | IEA | biological_process |
GO:0007268 | Synaptic transmission | TAS | biological_process |
GO:0016301 | Kinase activity | IDA | molecular_function |
GO:0019221 | Cytokine-mediated signaling pathway | TAS | biological_process |
GO:0030054 | Cell junction | IEA | cellular_component |
GO:0030666 | Endocytic vesicle membrane | TAS | cellular_component |
GO:0035254 | Glutamate receptor binding | IEA | molecular_function |
GO:0042734 | Presynaptic membrane | IEA | cellular_component |
GO:0046777 | Protein autophosphorylation | IEA | biological_process |
GO:0046928 | Regulation of neurotransmitter secretion | IEA | biological_process |
GO:0048168 | Regulation of neuronal synaptic plasticity | IEA | biological_process |
GO:0051092 | Positive regulation of NF-kappaB transcription factor activity | IMP | biological_process |
GO:0060333 | Interferon-gamma-mediated signaling pathway | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
p-value up | p-value down | FDR up | FDR down |
---|---|---|---|
0.7616253030 | 0.8355143953 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
Data source | Up or down | Log fold change |
---|---|---|
GSE11954 | Up | 0.0571261549 |
GSE13712_SHEAR | Down | -0.0902243961 |
GSE13712_STATIC | Down | -0.0214964149 |
GSE19018 | Up | 0.2129295568 |
GSE19899_A1 | Up | 0.0324444223 |
GSE19899_A2 | Down | -0.0417794310 |
PubMed_21979375_A1 | Up | 0.0494418045 |
PubMed_21979375_A2 | Down | -0.0243807163 |
GSE35957 | Down | -0.0190356778 |
GSE36640 | Down | -0.0636951652 |
GSE54402 | Down | -0.1375379957 |
GSE9593 | Down | -0.0084530346 |
GSE43922 | Up | 0.0375785505 |
GSE24585 | Down | -0.0563568310 |
GSE37065 | Down | -0.0425860171 |
GSE28863_A1 | Up | 0.0336915999 |
GSE28863_A2 | Up | 0.2207622874 |
GSE28863_A3 | Up | 0.0981378133 |
GSE28863_A4 | Up | 0.0919448995 |
GSE48662 | Down | -0.0181223939 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
---|---|---|
Hexatantalum Dodecabromide | DB04119 | EXPT03019 |
1,4-Dithiothreitol | DB04447 | EXPT01291 |
(2Z,3E)-2,3'-BIINDOLE-2',3(1H,1'H)-DIONE 3-{O-[(3R)-3,4-DIHYDROXYBUTYL]OXIME} | DB07766 | - |
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord