HCSGD entry for CAMK2A

1. General information

Official gene symbolCAMK2A
Entrez ID815
Gene full namecalcium/calmodulin-dependent protein kinase II alpha
Other gene symbolsCAMKA
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000082G1/S transition of mitotic cell cycleIEAbiological_process
GO:0004674Protein serine/threonine kinase activityIEAmolecular_function
GO:0004683Calmodulin-dependent protein kinase activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005516Calmodulin bindingIEAmolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005654NucleoplasmTAScellular_component
GO:0005829CytosolTAScellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0006468Protein phosphorylationIDAbiological_process
GO:0006816Calcium ion transportIEAbiological_process
GO:0007268Synaptic transmissionTASbiological_process
GO:0016301Kinase activityIDAmolecular_function
GO:0019221Cytokine-mediated signaling pathwayTASbiological_process
GO:0030054Cell junctionIEAcellular_component
GO:0030666Endocytic vesicle membraneTAScellular_component
GO:0035254Glutamate receptor bindingIEAmolecular_function
GO:0042734Presynaptic membraneIEAcellular_component
GO:0046777Protein autophosphorylationIEAbiological_process
GO:0046928Regulation of neurotransmitter secretionIEAbiological_process
GO:0048168Regulation of neuronal synaptic plasticityIEAbiological_process
GO:0051092Positive regulation of NF-kappaB transcription factor activityIMPbiological_process
GO:0060333Interferon-gamma-mediated signaling pathwayTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.76162530300.83551439530.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0571261549
GSE13712_SHEARDown-0.0902243961
GSE13712_STATICDown-0.0214964149
GSE19018Up0.2129295568
GSE19899_A1Up0.0324444223
GSE19899_A2Down-0.0417794310
PubMed_21979375_A1Up0.0494418045
PubMed_21979375_A2Down-0.0243807163
GSE35957Down-0.0190356778
GSE36640Down-0.0636951652
GSE54402Down-0.1375379957
GSE9593Down-0.0084530346
GSE43922Up0.0375785505
GSE24585Down-0.0563568310
GSE37065Down-0.0425860171
GSE28863_A1Up0.0336915999
GSE28863_A2Up0.2207622874
GSE28863_A3Up0.0981378133
GSE28863_A4Up0.0919448995
GSE48662Down-0.0181223939

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

Hexatantalum DodecabromideDB04119 EXPT03019
1,4-DithiothreitolDB04447 EXPT01291
(2Z,3E)-2,3'-BIINDOLE-2',3(1H,1'H)-DIONE 3-{O-[(3R)-3,4-DIHYDROXYBUTYL]OXIME}DB07766 -

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.