HCSGD entry for CAMK4

1. General information

Official gene symbolCAMK4
Entrez ID814
Gene full namecalcium/calmodulin-dependent protein kinase IV
Other gene symbolsCaMK IV CaMK-GR IV caMK
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0002372Myeloid dendritic cell cytokine productionIMPbiological_process
GO:0004672Protein kinase activityIEAmolecular_function
GO:0004683Calmodulin-dependent protein kinase activityIEAmolecular_function
GO:0005516Calmodulin bindingIEAmolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005634NucleusIDA IEAcellular_component
GO:0005654NucleoplasmTAScellular_component
GO:0005730NucleolusIDAcellular_component
GO:0005737CytoplasmIEAcellular_component
GO:0005829CytosolTAScellular_component
GO:0006468Protein phosphorylationTASbiological_process
GO:0006913Nucleocytoplasmic transportIEAbiological_process
GO:0006954Inflammatory responseIEAbiological_process
GO:0007165Signal transductionIEA TASbiological_process
GO:0007173Epidermal growth factor receptor signaling pathwayTASbiological_process
GO:0007202Activation of phospholipase C activityTASbiological_process
GO:0007268Synaptic transmissionTASbiological_process
GO:0007270Neuron-neuron synaptic transmissionIEAbiological_process
GO:0007616Long-term memoryIGIbiological_process
GO:0008543Fibroblast growth factor receptor signaling pathwayTASbiological_process
GO:0033081Regulation of T cell differentiation in thymusTASbiological_process
GO:0043011Myeloid dendritic cell differentiationIMPbiological_process
GO:0045087Innate immune responseTASbiological_process
GO:0045670Regulation of osteoclast differentiationTASbiological_process
GO:0045893Positive regulation of transcription, DNA-templatedIDA IEAbiological_process
GO:0046827Positive regulation of protein export from nucleusIEAbiological_process
GO:0048011Neurotrophin TRK receptor signaling pathwayTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.99773467950.00518446490.99999024730.1460320856

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.2074100145
GSE13712_SHEARDown-0.1422190271
GSE13712_STATICDown-0.1455506886
GSE19018Down-0.2273451047
GSE19899_A1Down-0.0596531410
GSE19899_A2Down-1.2955891941
PubMed_21979375_A1Down-0.5361388474
PubMed_21979375_A2Down-0.8337094293
GSE35957Down-0.1242931622
GSE36640Down-1.4241530112
GSE54402Down-0.5870875797
GSE9593Down-0.1514620702
GSE43922Down-0.8380868860
GSE24585Down-0.3802952600
GSE37065Down-0.1593904597
GSE28863_A1Down-0.0716088911
GSE28863_A2Down-0.4845312080
GSE28863_A3Up0.0931432783
GSE28863_A4Down-0.1604400840
GSE48662Down-0.0463476751

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

5-AMINO-3-{[4-(AMINOSULFONYL)PHENYL]AMINO}-N-(2,6-DIFLUOROPHENYL)-1H-1,2,4-TRIAZOLE-1-CARBOTHIOAMIDEDB07664 -
3-({[(3S)-3,4-dihydroxybutyl]oxy}amino)-1H,2'H-2,3'-biindol-2'-oneDB07676 -

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-215-5pMIMAT0000272MIRT024679MicroarrayFunctional MTI (Weak)19074876
hsa-miR-192-5pMIMAT0000222MIRT026869MicroarrayFunctional MTI (Weak)19074876
hsa-miR-26b-5pMIMAT0000083MIRT030257MicroarrayFunctional MTI (Weak)19088304
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.