HCSGD entry for CAMK4

1. General information

Official gene symbolCAMK4
Entrez ID814
Gene full namecalcium/calmodulin-dependent protein kinase IV
Other gene symbolsCaMK IV CaMK-GR IV caMK
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0002372Myeloid dendritic cell cytokine productionIMPbiological_process
GO:0004672Protein kinase activityIEAmolecular_function
GO:0004683Calmodulin-dependent protein kinase activityIEAmolecular_function
GO:0005516Calmodulin bindingIEAmolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005634NucleusIDA IEAcellular_component
GO:0005654NucleoplasmTAScellular_component
GO:0005730NucleolusIDAcellular_component
GO:0005737CytoplasmIEAcellular_component
GO:0005829CytosolTAScellular_component
GO:0006468Protein phosphorylationTASbiological_process
GO:0006913Nucleocytoplasmic transportIEAbiological_process
GO:0006954Inflammatory responseIEAbiological_process
GO:0007165Signal transductionIEA TASbiological_process
GO:0007173Epidermal growth factor receptor signaling pathwayTASbiological_process
GO:0007202Activation of phospholipase C activityTASbiological_process
GO:0007268Synaptic transmissionTASbiological_process
GO:0007270Neuron-neuron synaptic transmissionIEAbiological_process
GO:0007616Long-term memoryIGIbiological_process
GO:0008543Fibroblast growth factor receptor signaling pathwayTASbiological_process
GO:0033081Regulation of T cell differentiation in thymusTASbiological_process
GO:0043011Myeloid dendritic cell differentiationIMPbiological_process
GO:0045087Innate immune responseTASbiological_process
GO:0045670Regulation of osteoclast differentiationTASbiological_process
GO:0045893Positive regulation of transcription, DNA-templatedIDA IEAbiological_process
GO:0046827Positive regulation of protein export from nucleusIEAbiological_process
GO:0048011Neurotrophin TRK receptor signaling pathwayTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.99773467950.00518446490.99999024730.1460320856

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.2074100145
GSE13712_SHEARDown-0.1422190271
GSE13712_STATICDown-0.1455506886
GSE19018Down-0.2273451047
GSE19899_A1Down-0.0596531410
GSE19899_A2Down-1.2955891941
PubMed_21979375_A1Down-0.5361388474
PubMed_21979375_A2Down-0.8337094293
GSE35957Down-0.1242931622
GSE36640Down-1.4241530112
GSE54402Down-0.5870875797
GSE9593Down-0.1514620702
GSE43922Down-0.8380868860
GSE24585Down-0.3802952600
GSE37065Down-0.1593904597
GSE28863_A1Down-0.0716088911
GSE28863_A2Down-0.4845312080
GSE28863_A3Up0.0931432783
GSE28863_A4Down-0.1604400840
GSE48662Down-0.0463476751

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

5-AMINO-3-{[4-(AMINOSULFONYL)PHENYL]AMINO}-N-(2,6-DIFLUOROPHENYL)-1H-1,2,4-TRIAZOLE-1-CARBOTHIOAMIDEDB07664 -
3-({[(3S)-3,4-dihydroxybutyl]oxy}amino)-1H,2'H-2,3'-biindol-2'-oneDB07676 -

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-215-5pMIMAT0000272MIRT024679MicroarrayFunctional MTI (Weak)19074876
hsa-miR-192-5pMIMAT0000222MIRT026869MicroarrayFunctional MTI (Weak)19074876
hsa-miR-26b-5pMIMAT0000083MIRT030257MicroarrayFunctional MTI (Weak)19088304
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.