HCSGD entry for ST8SIA2

1. General information

Official gene symbolST8SIA2
Entrez ID8128
Gene full nameST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
Other gene symbolsHsT19690 SIAT8B ST8SIA-II STX
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000139Golgi membraneTAScellular_component
GO:0001574Ganglioside biosynthetic processIDAbiological_process
GO:0003828Alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activityIDAmolecular_function
GO:0005975Carbohydrate metabolic processTASbiological_process
GO:0006464Cellular protein modification processTASbiological_process
GO:0006486Protein glycosylationIDA IEAbiological_process
GO:0006491N-glycan processingIDAbiological_process
GO:0007399Nervous system developmentTASbiological_process
GO:0007411Axon guidanceTASbiological_process
GO:0008373Sialyltransferase activityIEAmolecular_function
GO:0009311Oligosaccharide metabolic processIDAbiological_process
GO:0018279Protein N-linked glycosylation via asparagineTASbiological_process
GO:0030173Integral component of Golgi membraneIEAcellular_component
GO:0033691Sialic acid bindingICmolecular_function
GO:0043687Post-translational protein modificationTASbiological_process
GO:0044267Cellular protein metabolic processTASbiological_process
GO:0097503SialylationIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.84837758440.61338329470.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0649570151
GSE13712_SHEARDown-0.3537940247
GSE13712_STATICDown-0.2678266339
GSE19018Down-0.0097293115
GSE19899_A1Up0.1552206897
GSE19899_A2Up0.0781901926
PubMed_21979375_A1Up0.0472465983
PubMed_21979375_A2Down-0.0170478323
GSE35957Up0.0548303403
GSE36640Down-0.0164722565
GSE54402Up0.0012072017
GSE9593Up0.0315656508
GSE43922Up0.0703737665
GSE24585Down-0.1970004646
GSE37065Down-0.0946256708
GSE28863_A1Up0.0425264299
GSE28863_A2Up0.1178542201
GSE28863_A3Up0.1054608469
GSE28863_A4Down-0.0327778288
GSE48662Down-0.0654700234

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-26b-5pMIMAT0000083MIRT029111MicroarrayFunctional MTI (Weak)19088304
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.