HCSGD entry for ST8SIA2


1. General information

Official gene symbolST8SIA2
Entrez ID8128
Gene full nameST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
Other gene symbolsHsT19690 SIAT8B ST8SIA-II STX
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000139Golgi membraneTAScellular_component
GO:0001574Ganglioside biosynthetic processIDAbiological_process
GO:0003828Alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activityIDAmolecular_function
GO:0005975Carbohydrate metabolic processTASbiological_process
GO:0006464Cellular protein modification processTASbiological_process
GO:0006486Protein glycosylationIDA IEAbiological_process
GO:0006491N-glycan processingIDAbiological_process
GO:0007399Nervous system developmentTASbiological_process
GO:0007411Axon guidanceTASbiological_process
GO:0008373Sialyltransferase activityIEAmolecular_function
GO:0009311Oligosaccharide metabolic processIDAbiological_process
GO:0018279Protein N-linked glycosylation via asparagineTASbiological_process
GO:0030173Integral component of Golgi membraneIEAcellular_component
GO:0033691Sialic acid bindingICmolecular_function
GO:0043687Post-translational protein modificationTASbiological_process
GO:0044267Cellular protein metabolic processTASbiological_process
GO:0097503SialylationIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.84837758440.61338329470.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0649570151
GSE13712_SHEARDown-0.3537940247
GSE13712_STATICDown-0.2678266339
GSE19018Down-0.0097293115
GSE19899_A1Up0.1552206897
GSE19899_A2Up0.0781901926
PubMed_21979375_A1Up0.0472465983
PubMed_21979375_A2Down-0.0170478323
GSE35957Up0.0548303403
GSE36640Down-0.0164722565
GSE54402Up0.0012072017
GSE9593Up0.0315656508
GSE43922Up0.0703737665
GSE24585Down-0.1970004646
GSE37065Down-0.0946256708
GSE28863_A1Up0.0425264299
GSE28863_A2Up0.1178542201
GSE28863_A3Up0.1054608469
GSE28863_A4Down-0.0327778288
GSE48662Down-0.0654700234

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-26b-5pMIMAT0000083MIRT029111MicroarrayFunctional MTI (Weak)19088304
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.