HCSGD entry for GLRA3

1. General information

Official gene symbolGLRA3
Entrez ID8001
Gene full nameglycine receptor, alpha 3
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneIEAcellular_component
GO:0016594Glycine bindingIEAmolecular_function
GO:0016934Extracellular-glycine-gated chloride channel activityIEAmolecular_function
GO:0022824Transmitter-gated ion channel activityIEAmolecular_function
GO:0030054Cell junctionIEAcellular_component
GO:0034220Ion transmembrane transportTASbiological_process
GO:0034707Chloride channel complexIEAcellular_component
GO:0045211Postsynaptic membraneIEAcellular_component
GO:0055085Transmembrane transportTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.69490371190.91703409440.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0433735452
GSE13712_SHEARUp0.0177821744
GSE13712_STATICUp0.0651693986
GSE19018Up0.0514404941
GSE19899_A1Down-0.0595360815
GSE19899_A2Up0.0054899903
PubMed_21979375_A1Up0.1329884301
PubMed_21979375_A2Up0.0268158898
GSE35957Up0.0771057388
GSE36640Down-0.0063753836
GSE54402Up0.0249957054
GSE9593Down-0.0186881157
GSE43922Up0.1289058953
GSE24585Up0.1467243013
GSE37065Down-0.0328630976
GSE28863_A1Down-0.0081312008
GSE28863_A2Up0.0473532909
GSE28863_A3Up0.0937655154
GSE28863_A4Down-0.0225705040
GSE48662Up0.0235929859

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

GlycineDB00145 NUTR00028
PicrotoxinDB00466 APRD00269
IvermectinDB00602 APRD01058

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.