HCSGD entry for PHF17
1. General information
| Official gene symbol | PHF17 |
|---|---|
| Entrez ID | 79960 |
| Gene full name | PHD finger protein 17 |
| Other gene symbols | JADE1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000123 | Histone acetyltransferase complex | IDA | cellular_component |
| GO:0001105 | RNA polymerase II transcription coactivator activity | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005739 | Mitochondrion | IDA | cellular_component |
| GO:0005886 | Plasma membrane | IDA | cellular_component |
| GO:0006357 | Regulation of transcription from RNA polymerase II promoter | IDA | biological_process |
| GO:0006366 | Transcription from RNA polymerase II promoter | IDA | biological_process |
| GO:0006915 | Apoptotic process | NAS | biological_process |
| GO:0006950 | Response to stress | NAS | biological_process |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0030308 | Negative regulation of cell growth | NAS | biological_process |
| GO:0043966 | Histone H3 acetylation | IDA | biological_process |
| GO:0043981 | Histone H4-K5 acetylation | IDA | biological_process |
| GO:0043982 | Histone H4-K8 acetylation | IDA | biological_process |
| GO:0043983 | Histone H4-K12 acetylation | IDA | biological_process |
| GO:0043984 | Histone H4-K16 acetylation | IDA | biological_process |
| GO:0045944 | Positive regulation of transcription from RNA polymerase II promoter | IDA | biological_process |
| GO:2000134 | Negative regulation of G1/S transition of mitotic cell cycle | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8382989362 | 0.0012163216 | 0.9999902473 | 0.0662832298 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -1.4647571160 |
| GSE13712_SHEAR | Down | -0.7528339403 |
| GSE13712_STATIC | Down | -0.0366621544 |
| GSE19018 | Up | 0.2023713691 |
| GSE19899_A1 | Down | -1.0904272648 |
| GSE19899_A2 | Down | -2.3169604041 |
| PubMed_21979375_A1 | Down | -1.6934982260 |
| PubMed_21979375_A2 | Down | -2.1031007115 |
| GSE35957 | Up | 1.3576696645 |
| GSE36640 | Down | -2.1163974976 |
| GSE54402 | Down | -2.0795582095 |
| GSE9593 | Up | 0.2579055094 |
| GSE43922 | Down | -0.8109468439 |
| GSE24585 | Down | -0.0233956548 |
| GSE37065 | Down | -0.3321837028 |
| GSE28863_A1 | Up | 0.2263947561 |
| GSE28863_A2 | Up | 0.3397619520 |
| GSE28863_A3 | Up | 0.1829287112 |
| GSE28863_A4 | Down | -0.0148118442 |
| GSE48662 | Down | -0.3737309317 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT001806 | Luciferase reporter assay//Reporter assay;Other | Non-Functional MTI | 17881434 |
| hsa-miR-145-5p | MIMAT0000437 | MIRT021530 | Reporter assay;Microarray | Functional MTI | 21351259 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT022313 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026279 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-21-5p | MIMAT0000076 | MIRT030770 | Microarray | Functional MTI (Weak) | 18591254 |
| hsa-miR-342-5p | MIMAT0004694 | MIRT038204 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-324-3p | MIMAT0000762 | MIRT042863 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
