HCSGD entry for PHF17


1. General information

Official gene symbolPHF17
Entrez ID79960
Gene full namePHD finger protein 17
Other gene symbolsJADE1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000123Histone acetyltransferase complexIDAcellular_component
GO:0001105RNA polymerase II transcription coactivator activityIDAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005739MitochondrionIDAcellular_component
GO:0005886Plasma membraneIDAcellular_component
GO:0006357Regulation of transcription from RNA polymerase II promoterIDAbiological_process
GO:0006366Transcription from RNA polymerase II promoterIDAbiological_process
GO:0006915Apoptotic processNASbiological_process
GO:0006950Response to stressNASbiological_process
GO:0008270Zinc ion bindingIEAmolecular_function
GO:0030308Negative regulation of cell growthNASbiological_process
GO:0043966Histone H3 acetylationIDAbiological_process
GO:0043981Histone H4-K5 acetylationIDAbiological_process
GO:0043982Histone H4-K8 acetylationIDAbiological_process
GO:0043983Histone H4-K12 acetylationIDAbiological_process
GO:0043984Histone H4-K16 acetylationIDAbiological_process
GO:0045944Positive regulation of transcription from RNA polymerase II promoterIDAbiological_process
GO:2000134Negative regulation of G1/S transition of mitotic cell cycleIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.83829893620.00121632160.99999024730.0662832298

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-1.4647571160
GSE13712_SHEARDown-0.7528339403
GSE13712_STATICDown-0.0366621544
GSE19018Up0.2023713691
GSE19899_A1Down-1.0904272648
GSE19899_A2Down-2.3169604041
PubMed_21979375_A1Down-1.6934982260
PubMed_21979375_A2Down-2.1031007115
GSE35957Up1.3576696645
GSE36640Down-2.1163974976
GSE54402Down-2.0795582095
GSE9593Up0.2579055094
GSE43922Down-0.8109468439
GSE24585Down-0.0233956548
GSE37065Down-0.3321837028
GSE28863_A1Up0.2263947561
GSE28863_A2Up0.3397619520
GSE28863_A3Up0.1829287112
GSE28863_A4Down-0.0148118442
GSE48662Down-0.3737309317

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-155-5pMIMAT0000646MIRT001806Luciferase reporter assay//Reporter assay;OtherNon-Functional MTI17881434
hsa-miR-145-5pMIMAT0000437MIRT021530Reporter assay;MicroarrayFunctional MTI21351259
hsa-miR-124-3pMIMAT0000422MIRT022313MicroarrayFunctional MTI (Weak)18668037
hsa-miR-192-5pMIMAT0000222MIRT026279MicroarrayFunctional MTI (Weak)19074876
hsa-miR-21-5pMIMAT0000076MIRT030770MicroarrayFunctional MTI (Weak)18591254
hsa-miR-342-5pMIMAT0004694MIRT038204CLASHFunctional MTI (Weak)23622248
hsa-miR-324-3pMIMAT0000762MIRT042863CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.