HCSGD entry for ALS2CR8
1. General information
| Official gene symbol | ALS2CR8 |
|---|---|
| Entrez ID | 79800 |
| Gene full name | amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 8 |
| Other gene symbols | CARF NYD-SP24 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003677 | DNA binding | IDA IEA | molecular_function |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | IDA IEA | molecular_function |
| GO:0005634 | Nucleus | ISS | cellular_component |
| GO:0005654 | Nucleoplasm | IEA | cellular_component |
| GO:0005730 | Nucleolus | IEA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0035865 | Cellular response to potassium ion | IDA | biological_process |
| GO:0061400 | Positive regulation of transcription from RNA polymerase II promoter in response to calcium ion | IDA IEA | biological_process |
| GO:0071277 | Cellular response to calcium ion | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2828120892 | 0.7133448653 | 0.9815265032 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1253872943 |
| GSE13712_SHEAR | Down | -0.1646262177 |
| GSE13712_STATIC | Up | 0.0610834518 |
| GSE19018 | Up | 0.1141939323 |
| GSE19899_A1 | Up | 0.0451018198 |
| GSE19899_A2 | Up | 0.1648439503 |
| PubMed_21979375_A1 | Up | 0.1699958288 |
| PubMed_21979375_A2 | Down | -0.1077452288 |
| GSE35957 | Up | 0.0899894252 |
| GSE36640 | Up | 0.4071347125 |
| GSE54402 | Down | -0.2789248593 |
| GSE9593 | Up | 0.2691951051 |
| GSE43922 | Down | -0.1323197894 |
| GSE24585 | Up | 1.0800876767 |
| GSE37065 | Up | 0.0874311869 |
| GSE28863_A1 | Down | -0.1273382069 |
| GSE28863_A2 | Up | 0.0516587317 |
| GSE28863_A3 | Down | -0.0590900792 |
| GSE28863_A4 | Down | -0.1960839418 |
| GSE48662 | Down | -0.0576901763 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-34a-5p | MIMAT0000255 | MIRT025457 | Proteomics | Functional MTI (Weak) | 21566225 |
| hsa-miR-331-3p | MIMAT0000760 | MIRT043277 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
