HCSGD entry for ALS2CR8


1. General information

Official gene symbolALS2CR8
Entrez ID79800
Gene full nameamyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 8
Other gene symbolsCARF NYD-SP24
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003677DNA bindingIDA IEAmolecular_function
GO:0003700Sequence-specific DNA binding transcription factor activityIDA IEAmolecular_function
GO:0005634NucleusISScellular_component
GO:0005654NucleoplasmIEAcellular_component
GO:0005730NucleolusIEAcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0035865Cellular response to potassium ionIDAbiological_process
GO:0061400Positive regulation of transcription from RNA polymerase II promoter in response to calcium ionIDA IEAbiological_process
GO:0071277Cellular response to calcium ionIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.28281208920.71334486530.98152650321.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1253872943
GSE13712_SHEARDown-0.1646262177
GSE13712_STATICUp0.0610834518
GSE19018Up0.1141939323
GSE19899_A1Up0.0451018198
GSE19899_A2Up0.1648439503
PubMed_21979375_A1Up0.1699958288
PubMed_21979375_A2Down-0.1077452288
GSE35957Up0.0899894252
GSE36640Up0.4071347125
GSE54402Down-0.2789248593
GSE9593Up0.2691951051
GSE43922Down-0.1323197894
GSE24585Up1.0800876767
GSE37065Up0.0874311869
GSE28863_A1Down-0.1273382069
GSE28863_A2Up0.0516587317
GSE28863_A3Down-0.0590900792
GSE28863_A4Down-0.1960839418
GSE48662Down-0.0576901763

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-34a-5pMIMAT0000255MIRT025457ProteomicsFunctional MTI (Weak)21566225
hsa-miR-331-3pMIMAT0000760MIRT043277CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.