HCSGD entry for CARS2
1. General information
| Official gene symbol | CARS2 |
|---|---|
| Entrez ID | 79587 |
| Gene full name | cysteinyl-tRNA synthetase 2, mitochondrial (putative) |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004817 | Cysteine-tRNA ligase activity | IBA | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005759 | Mitochondrial matrix | IEA | cellular_component |
| GO:0005829 | Cytosol | IBA | cellular_component |
| GO:0006418 | TRNA aminoacylation for protein translation | TAS | biological_process |
| GO:0006423 | Cysteinyl-tRNA aminoacylation | IBA | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6864366817 | 0.6102901561 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0341839012 |
| GSE13712_SHEAR | Down | -0.0523427544 |
| GSE13712_STATIC | Up | 0.0287907966 |
| GSE19018 | Up | 0.1813471138 |
| GSE19899_A1 | Up | 0.0043705326 |
| GSE19899_A2 | Up | 0.3313229248 |
| PubMed_21979375_A1 | Up | 0.3641639210 |
| PubMed_21979375_A2 | Up | 0.3690880747 |
| GSE35957 | Down | -0.1276970607 |
| GSE36640 | Down | -0.0853363336 |
| GSE54402 | Up | 0.0551462657 |
| GSE9593 | Up | 0.0672355707 |
| GSE43922 | Up | 0.2846387720 |
| GSE24585 | Down | -0.2182136291 |
| GSE37065 | Down | -0.4381249372 |
| GSE28863_A1 | Down | -0.1269981570 |
| GSE28863_A2 | Down | -0.0320864830 |
| GSE28863_A3 | Down | -0.2862474598 |
| GSE28863_A4 | Up | 0.0183418336 |
| GSE48662 | Down | -0.1055026351 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| L-Cysteine | DB00151 | NUTR00018 | DB04443 |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT020814 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029604 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-30d-5p | MIMAT0000245 | MIRT047820 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
