HCSGD entry for CARS2


1. General information

Official gene symbolCARS2
Entrez ID79587
Gene full namecysteinyl-tRNA synthetase 2, mitochondrial (putative)
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004817Cysteine-tRNA ligase activityIBAmolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005759Mitochondrial matrixIEAcellular_component
GO:0005829CytosolIBAcellular_component
GO:0006418TRNA aminoacylation for protein translationTASbiological_process
GO:0006423Cysteinyl-tRNA aminoacylationIBAbiological_process
GO:0010467Gene expressionTASbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.68643668170.61029015610.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0341839012
GSE13712_SHEARDown-0.0523427544
GSE13712_STATICUp0.0287907966
GSE19018Up0.1813471138
GSE19899_A1Up0.0043705326
GSE19899_A2Up0.3313229248
PubMed_21979375_A1Up0.3641639210
PubMed_21979375_A2Up0.3690880747
GSE35957Down-0.1276970607
GSE36640Down-0.0853363336
GSE54402Up0.0551462657
GSE9593Up0.0672355707
GSE43922Up0.2846387720
GSE24585Down-0.2182136291
GSE37065Down-0.4381249372
GSE28863_A1Down-0.1269981570
GSE28863_A2Down-0.0320864830
GSE28863_A3Down-0.2862474598
GSE28863_A4Up0.0183418336
GSE48662Down-0.1055026351

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

L-CysteineDB00151 NUTR00018 | DB04443

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-155-5pMIMAT0000646MIRT020814ProteomicsFunctional MTI (Weak)18668040
hsa-miR-26b-5pMIMAT0000083MIRT029604MicroarrayFunctional MTI (Weak)19088304
hsa-miR-30d-5pMIMAT0000245MIRT047820CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.