HCSGD entry for MMP28


1. General information

Official gene symbolMMP28
Entrez ID79148
Gene full namematrix metallopeptidase 28
Other gene symbolsEPILYSIN MM28 MMP-28 MMP25
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004222Metalloendopeptidase activityTASmolecular_function
GO:0005509Calcium ion bindingIEAmolecular_function
GO:0005578Proteinaceous extracellular matrixNAScellular_component
GO:0006508ProteolysisIEAbiological_process
GO:0008237Metallopeptidase activityIEAmolecular_function
GO:0008270Zinc ion bindingIEAmolecular_function
GO:0046872Metal ion bindingIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.84873755180.53653153380.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0277970999
GSE13712_SHEARDown-0.6771643234
GSE13712_STATICDown-0.2081591534
GSE19018Up0.1228274929
GSE19899_A1Down-0.0816101669
GSE19899_A2Up0.0132094033
PubMed_21979375_A1Up0.1890051386
PubMed_21979375_A2Down-0.0949641377
GSE35957Up0.0580771237
GSE36640Up0.0824843237
GSE54402Down-0.0923493350
GSE9593Down-0.1448657012
GSE43922Up0.0224719121
GSE24585Up0.0542091443
GSE37065Down-0.0324757719
GSE28863_A1Up0.0004263946
GSE28863_A2Down-0.0200612055
GSE28863_A3Up0.3291506004
GSE28863_A4Down-0.0095983282
GSE48662Up0.2439201282

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

MarimastatDB00786 APRD00559

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.