HCSGD entry for MMP28
1. General information
| Official gene symbol | MMP28 |
|---|---|
| Entrez ID | 79148 |
| Gene full name | matrix metallopeptidase 28 |
| Other gene symbols | EPILYSIN MM28 MMP-28 MMP25 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004222 | Metalloendopeptidase activity | TAS | molecular_function |
| GO:0005509 | Calcium ion binding | IEA | molecular_function |
| GO:0005578 | Proteinaceous extracellular matrix | NAS | cellular_component |
| GO:0006508 | Proteolysis | IEA | biological_process |
| GO:0008237 | Metallopeptidase activity | IEA | molecular_function |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8487375518 | 0.5365315338 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0277970999 |
| GSE13712_SHEAR | Down | -0.6771643234 |
| GSE13712_STATIC | Down | -0.2081591534 |
| GSE19018 | Up | 0.1228274929 |
| GSE19899_A1 | Down | -0.0816101669 |
| GSE19899_A2 | Up | 0.0132094033 |
| PubMed_21979375_A1 | Up | 0.1890051386 |
| PubMed_21979375_A2 | Down | -0.0949641377 |
| GSE35957 | Up | 0.0580771237 |
| GSE36640 | Up | 0.0824843237 |
| GSE54402 | Down | -0.0923493350 |
| GSE9593 | Down | -0.1448657012 |
| GSE43922 | Up | 0.0224719121 |
| GSE24585 | Up | 0.0542091443 |
| GSE37065 | Down | -0.0324757719 |
| GSE28863_A1 | Up | 0.0004263946 |
| GSE28863_A2 | Down | -0.0200612055 |
| GSE28863_A3 | Up | 0.3291506004 |
| GSE28863_A4 | Down | -0.0095983282 |
| GSE48662 | Up | 0.2439201282 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Marimastat | DB00786 | APRD00559 |
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
