HCSGD entry for NPHS2

1. General information

Official gene symbolNPHS2
Entrez ID7827
Gene full namenephrosis 2, idiopathic, steroid-resistant (podocin)
Other gene symbolsPDCN SRN1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005515Protein bindingIPImolecular_function
GO:0005783Endoplasmic reticulumIEAcellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneIEAcellular_component
GO:0005911Cell-cell junctionIDAcellular_component
GO:0007588ExcretionIEAbiological_process
GO:0031235Intrinsic component of the cytoplasmic side of the plasma membraneIDAcellular_component
GO:0031532Actin cytoskeleton reorganizationIDAbiological_process
GO:0036057Slit diaphragmIDAcellular_component
GO:0043234Protein complexIDAcellular_component
GO:0045121Membrane raftIDAcellular_component
GO:0072249Metanephric glomerular visceral epithelial cell developmentIEPbiological_process
Entries Per Page
Displaying Page of

4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.69229653890.67912050830.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0130686383
GSE13712_SHEARDown-0.1585822311
GSE13712_STATICDown-0.2761387426
GSE19018Up0.1834690968
GSE19899_A1Up0.0076148483
GSE19899_A2Up0.0138144829
PubMed_21979375_A1Up0.0982060019
PubMed_21979375_A2Up0.1859012259
GSE35957Up0.1641818318
GSE36640Down-0.0466478268
GSE54402Up0.0732702025
GSE9593Down-0.1260112950
GSE43922Up0.0239821315
GSE24585Down-0.0915358790
GSE37065Down-0.1011736893
GSE28863_A1Down-0.0548592609
GSE28863_A2Down-0.0151108994
GSE28863_A3Up0.0832247868
GSE28863_A4Up0.1103401179
GSE48662Up0.2615995469

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT018421MicroarrayFunctional MTI (Weak)18185580
Entries Per Page
Displaying Page of
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.